Title:
ANTIBIOTIC FKI-1778 AND PROCESS FOR PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/2005/090326
Kind Code:
A1
Abstract:
A microorganism belonging to filamentous fungi, capable of producing antibiotic FKI-1778A and/or FKI-1778B and/or FKI-1778C and/or FKI-1778D is cultured in a culture medium to thereby accumulate the antibiotic FKI-1778A and/or FKI-1778B and/or FKI-1778C and/or FKI-1778D in the culture mixture. The antibiotic FKI-1778A and/or FKI-1778B and/or FKI-1778C and/or FKI-1778D is collected from the culture mixture. The thus obtained substance is promising as drugs, veterinary medicines or agrichemicals having a growth inhibiting activity to microorganisms, nematodes and arthropods or as drugs exhibiting a growth inhibiting activity to carcinoma cells.
Inventors:
OMURA SATOSHI (JP)
TOMODA HIROSHI (JP)
MASUMA ROKURO (JP)
TOMODA HIROSHI (JP)
MASUMA ROKURO (JP)
Application Number:
PCT/JP2004/004137
Publication Date:
September 29, 2005
Filing Date:
March 24, 2004
Export Citation:
Assignee:
KITASATO INST (JP)
OMURA SATOSHI (JP)
TOMODA HIROSHI (JP)
MASUMA ROKURO (JP)
OMURA SATOSHI (JP)
TOMODA HIROSHI (JP)
MASUMA ROKURO (JP)
International Classes:
A61K31/366; A61P33/00; A61P35/00; C07D309/38; C12P17/06; (IPC1-7): C07D309/38; C12P17/06; A61K31/366; A61P33/00; A61P35/00
Domestic Patent References:
| WO1995006646A1 | 1995-03-09 |
Foreign References:
| JPH0856688A | 1996-03-05 | |||
| DE2316429A1 | 1973-10-11 |
Other References:
TOMODA H. ET AL: "Itojokin Albophoma sp. ga Seisan suru Shinki Sacchu Kassei Busshitsu sesquicillin Kanren Kagobutsugun no Tanri, Kozo Kettei oyobi Seibutsu Kassei", THE PHARMACEUTICAL SOCIETY OF JAPAN, DAI 124 NENKAI YOSHISHU, 5 March 2004 (2004-03-05), pages 150 - 31 P2 I -413, XP002996298
JEONG H.W. ET AL: "Biological effects of G1 phase arrest compound, sesquicillin, in human breast cancer cell lines", BIOORG.MED.CHEM., vol. 10, no. 1, 2002, pages 3129 - 3134, XP002979667
JEONG H.W. ET AL: "Biological effects of G1 phase arrest compound, sesquicillin, in human breast cancer cell lines", BIOORG.MED.CHEM., vol. 10, no. 1, 2002, pages 3129 - 3134, XP002979667
Attorney, Agent or Firm:
Kobayashi, Kazunori (25-1 Kitaotsuka 2-chom, Toshima-ku Tokyo, JP)
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