Title:
ANTIBIOTIC NANOMATERIAL
Document Type and Number:
WIPO Patent Application WO/2010/063998
Kind Code:
A3
Abstract:
The invention provides a composition comprising nanoparticles, which nanoparticles comprise Allicin and an inorganic carrier. Further provided is a process for producing the composition of the invention, the process comprising treating precursor nanoparticles, comprising said inorganic carrier, with Allicin. The composition of the invention may be used as an antimicrobial agent or for treating a bacterial infection, a fungal infection, a viral infection, an infection by a pathogenic protozoan, a tumour, cancer or thrombosis, or to stimulate or enhance the immune system. The invention further provides antimicrobial films, coatings, coated products, packaging materials, and polymer compositions, all of which comprise said nanoparticles, and processes for producing the films, coatings and coated products.
Inventors:
THOMPSON IAN (GB)
MOLINA FRANCISCO RODRIGO (GB)
DOBSON PETER (GB)
MOLINA FRANCISCO RODRIGO (GB)
DOBSON PETER (GB)
Application Number:
PCT/GB2009/002795
Publication Date:
December 29, 2010
Filing Date:
December 01, 2009
Export Citation:
Assignee:
ISIS INNOVATION (GB)
THOMPSON IAN (GB)
MOLINA FRANCISCO RODRIGO (GB)
DOBSON PETER (GB)
THOMPSON IAN (GB)
MOLINA FRANCISCO RODRIGO (GB)
DOBSON PETER (GB)
International Classes:
A61K47/48; A01N25/08; A01N25/34; A01N41/08; A01N65/42; A01P1/00; A01P3/00; A61K9/00; A61K9/20
Domestic Patent References:
| WO2007015105A2 | 2007-02-08 |
Foreign References:
| EP0305968A2 | 1989-03-08 | |||
| US5556699A | 1996-09-17 |
Other References:
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 20 January 2006 (2006-01-20), HE, RONGQIAO; YANG, JIARONG; HE, JIAN: "Single particle nanoallicin capsule and its preparation", XP002606677, Database accession no. 144:135134
GU HONGWEI ET AL: "Presenting vancomycin on nanoparticles to enhance antimicrobial activities", NANO LETTERS, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/NL034396Z, vol. 3, no. 9, 1 January 2003 (2003-01-01), pages 1261 - 1263, XP002446943, ISSN: 1530-6984
NIRMALA GRACE ET AL: "Antibacterial efficacy of aminoglycosidic antibiotics protected gold nanoparticles-A brief study", COLLOIDS AND SURFACES. A, PHYSICACHEMICAL AND ENGINEERING ASPECTS, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/J.COLSURFA.2006.10.024, vol. 297, no. 1-3, 20 February 2007 (2007-02-20), pages 63 - 70, XP005895492, ISSN: 0927-7757
ROSEMARY M J ET AL: "Investigations of the antibacterial properties of ciprofloxacin@SiO2.", LANGMUIR : THE ACS JOURNAL OF SURFACES AND COLLOIDS 21 NOV 2006 LNKD- PUBMED:17107009, vol. 22, no. 24, 21 November 2006 (2006-11-21), pages 10125 - 10129, XP002606517, ISSN: 0743-7463
LUO PENGJU G ET AL: "Nanotechnology in the detection and control of microorganisms.", ADVANCES IN APPLIED MICROBIOLOGY 2008 LNKD- PUBMED:18395127, vol. 63, 3 April 2008 (2008-04-03), pages 145 - 181, XP008128245, ISSN: 0065-2164
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 9 December 2008 (2008-12-09), LIANG, JIAZHEN: "Bacteriostatic and deoxygenating food preservative and preparation method thereof", XP002606676, Database accession no. 150:54761
LUO DONG QING ET AL: "Anti-fungal efficacy of polybutylcyanoacrylate nanoparticles of allicin and comparison with pure allicin.", JOURNAL OF BIOMATERIALS SCIENCE. POLYMER EDITION 2009 LNKD- PUBMED:19105898, vol. 20, no. 1, 1 January 2009 (2009-01-01), pages 21 - 31, XP002606518, ISSN: 0920-5063
GU HONGWEI ET AL: "Presenting vancomycin on nanoparticles to enhance antimicrobial activities", NANO LETTERS, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/NL034396Z, vol. 3, no. 9, 1 January 2003 (2003-01-01), pages 1261 - 1263, XP002446943, ISSN: 1530-6984
NIRMALA GRACE ET AL: "Antibacterial efficacy of aminoglycosidic antibiotics protected gold nanoparticles-A brief study", COLLOIDS AND SURFACES. A, PHYSICACHEMICAL AND ENGINEERING ASPECTS, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/J.COLSURFA.2006.10.024, vol. 297, no. 1-3, 20 February 2007 (2007-02-20), pages 63 - 70, XP005895492, ISSN: 0927-7757
ROSEMARY M J ET AL: "Investigations of the antibacterial properties of ciprofloxacin@SiO2.", LANGMUIR : THE ACS JOURNAL OF SURFACES AND COLLOIDS 21 NOV 2006 LNKD- PUBMED:17107009, vol. 22, no. 24, 21 November 2006 (2006-11-21), pages 10125 - 10129, XP002606517, ISSN: 0743-7463
LUO PENGJU G ET AL: "Nanotechnology in the detection and control of microorganisms.", ADVANCES IN APPLIED MICROBIOLOGY 2008 LNKD- PUBMED:18395127, vol. 63, 3 April 2008 (2008-04-03), pages 145 - 181, XP008128245, ISSN: 0065-2164
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 9 December 2008 (2008-12-09), LIANG, JIAZHEN: "Bacteriostatic and deoxygenating food preservative and preparation method thereof", XP002606676, Database accession no. 150:54761
LUO DONG QING ET AL: "Anti-fungal efficacy of polybutylcyanoacrylate nanoparticles of allicin and comparison with pure allicin.", JOURNAL OF BIOMATERIALS SCIENCE. POLYMER EDITION 2009 LNKD- PUBMED:19105898, vol. 20, no. 1, 1 January 2009 (2009-01-01), pages 21 - 31, XP002606518, ISSN: 0920-5063
Attorney, Agent or Firm:
SILCOCK, Peter, James et al. (14 South SquareGray's Inn, London WC1R 5JJ, GB)
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