Title:
ANTIBODY WHICH SPECIFICALLY BINDS TO HUMAN CRTH2
Document Type and Number:
WIPO Patent Application WO2017010567
Kind Code:
A1
Abstract:
The present invention pertains to: an anti-human CRTH2 antibody which specifically recognizes and binds to human CRTH2; a fragment of the antibody; DNA which encodes the amino acid sequence of the antibody; a vector including the DNA; an antibody-producing cell and a hybridoma which produce the antibody; a production method for the antibody; a composition which includes the antibody or antibody fragment; a treatment method and a diagnostic method which use the antibody or antibody fragment for diseases, such as allergenic diseases, autoimmune diseases, diseases associated with eosinophilia and hyperfunction, and diseases associated with an increase in and/or hyperfunction of Th2 cells; and a medicine and a diagnostic agent which include the antibody or antibody fragment.
Inventors:
KAMEYAMA NAOYA (JP)
ANDO MUNETOSHI (JP)
OGAWA SHINYA (JP)
OKADA KAZUKI (JP)
ANDO MUNETOSHI (JP)
OGAWA SHINYA (JP)
OKADA KAZUKI (JP)
Application Number:
PCT/JP2016/071027
Publication Date:
January 19, 2017
Filing Date:
July 15, 2016
Export Citation:
Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
International Classes:
C07K16/28; A61K39/395; A61P29/00; A61P37/02; A61P37/06; A61P37/08; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/02; C12N15/09; C12P21/08; G01N33/53; G01N33/531
Domestic Patent References:
| WO2014144865A2 | 2014-09-18 | |||
| WO1997046677A1 | 1997-12-11 | |||
| WO2005093092A2 | 2005-10-06 |
Other References:
NAGATA, K. ET AL.: "Selective expression of a novel surface molecule by human Th2 cells in vivo", J. IMMUNOL., vol. 162, no. 3, 1999, pages 1278 - 1286, XP055121136, ISSN: 0022-1767
"CRTH-2/GPR44 Antibody FAB33381N", NOVUS BIOLOGICALS, 26 June 2015 (2015-06-26), XP009508385, Retrieved from the Internet [retrieved on 20161004]
"Human CRTH-2 Antibody", R&D SYSTEMS, INC., 13 March 2015 (2015-03-13), XP009508383, Retrieved from the Internet [retrieved on 20161004]
See also references of EP 3323832A4
"CRTH-2/GPR44 Antibody FAB33381N", NOVUS BIOLOGICALS, 26 June 2015 (2015-06-26), XP009508385, Retrieved from the Internet
"Human CRTH-2 Antibody", R&D SYSTEMS, INC., 13 March 2015 (2015-03-13), XP009508383, Retrieved from the Internet
See also references of EP 3323832A4
Attorney, Agent or Firm:
Eikoh Patent Firm, P.C. (JP)
Download PDF:
Previous Patent: POLYAMIC ACID SOLUTION COMPOSITION AND POLYIMIDE FILM
Next Patent: RNA-PROTEIN COMPLEX AND USE THEREOF
Next Patent: RNA-PROTEIN COMPLEX AND USE THEREOF