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Title:
ANTICANER AGENTS
Document Type and Number:
WIPO Patent Application WO/2003/041739
Kind Code:
A1
Abstract:
Remedies&sol preventives for hormone−independent cancer, hormone−independent cancer cell proliferation inhibitors, apoptosis inducers for cancer cells, etc. each containing a compound having an angiotensin II antagonism, its prodrug or a salt thereof. Thus, excellent anticancer agents are provided.

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Inventors:
KUBOTA YOSHINOBU (JP)
UEMURA HIROSHI (JP)
NAKAIGAWA NOBORU (JP)
NAITO KENICHIRO (JP)
Application Number:
PCT/JP2002/011780
Publication Date:
May 22, 2003
Filing Date:
November 12, 2002
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
KUBOTA YOSHINOBU (JP)
UEMURA HIROSHI (JP)
NAKAIGAWA NOBORU (JP)
NAITO KENICHIRO (JP)
International Classes:
A61K31/41; A61K31/4178; A61K31/4184; A61K31/4245; A61K31/519; A61K31/522; A61K38/08; A61K38/09; A61K45/06; A61P35/00; A61P43/00; (IPC1-7): A61K45/00; A61K31/41; A61K31/4178; A61K31/4184; A61K31/522; A61K38/00; A61P35/00; A61P43/00
Domestic Patent References:
WO1999044590A11999-09-10
WO2001060410A12001-08-23
WO2000038676A12000-07-06
WO1991000027A11991-01-10
WO1991018016A11991-11-28
WO1998003505A21998-01-29
WO2001077107A12001-10-18
WO1999036099A11999-07-22
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Other References:
FUJIMOTO Y. ET AL.: "Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist", FEBS LETTERS, vol. 495, no. 3, 2001, pages 197 - 200, XP002963741
See also references of EP 1444988A4
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JAPAN CLINIC, vol. 54, no. 7, 1996
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Attorney, Agent or Firm:
Takahashi, Shuichi c/o Osaka Plant of TAKEDA CHEMICAL INDUSTRIES LTD. (17-85, Jusohonmachi 2-chome, Yodogawa-k, Osaka-shi Osaka, JP)
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