Title:
ANTICOAGULANT PENTASACCHARIDE COMPOUND, COMPOSITION, AND PREPARATION METHOD AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/114418
Kind Code:
A1
Abstract:
The present invention relates to an anticoagulant compound having an anionic form represented by formula (A), a preparation method thereof, and a use of the same in preparing a drug for preventing and/or treating a disease related to coagulopathy.
Inventors:
ZHANG LINLIN (CN)
FENG HAIWEI (CN)
ZHAO JIANLIANG (CN)
WU YOUZHI (CN)
WU JIAN (CN)
MA CHANGYOU (CN)
CHAI YUZHU (CN)
WANG HUAPING (CN)
XU DAN (CN)
ZHU CHUNXIA (CN)
TIAN ZHOUSHAN (CN)
WU MINGYI (CN)
FENG HAIWEI (CN)
ZHAO JIANLIANG (CN)
WU YOUZHI (CN)
WU JIAN (CN)
MA CHANGYOU (CN)
CHAI YUZHU (CN)
WANG HUAPING (CN)
XU DAN (CN)
ZHU CHUNXIA (CN)
TIAN ZHOUSHAN (CN)
WU MINGYI (CN)
Application Number:
PCT/CN2019/122954
Publication Date:
June 11, 2020
Filing Date:
December 04, 2019
Export Citation:
Assignee:
NANJING CHIA TAI TIANQING PHARMACEUTICAL CO LTD (CN)
International Classes:
C07H15/04; A61K31/7028; A61P7/02; A61P9/10; A61P11/00; A61P29/00; C07H1/00; C07H15/18
Foreign References:
| US5543403A | 1996-08-06 | |||
| CN109134554A | 2019-01-04 | |||
| CN109134553A | 2019-01-04 | |||
| CN109134555A | 2019-01-04 |
Other References:
P WESTERDUIN ET AL: "Feasible Synthesis and Biological Properties of Six ‘Non-Glycosamino’ Glycan Analogues of the Antithrombin III Binding Heparin Pentasaccharide", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 2, no. 11, 1 November 1994 (1994-11-01), pages 1267 - 1280, XP026630310, ISSN: 0968-0896, DOI: 10.1016/S0968-0896(00)82078-7
J.È HERAULT ET AL: "Pharmacokinetic Study of Three Synthetic AT-binding Pentasaccharides in Various Animal Species-extrapolation to Humans", BLOOD COAGULATION & FIBRINOLYSIS, vol. 8, no. 3, 1 January 1997 (1997-01-01), pages 161 - 167, XP001070290, ISSN: 0957-5235, DOI: 10.1097/00001721-199704000-00002
J.È HERAULT ET AL: "Pharmacokinetic Study of Three Synthetic AT-binding Pentasaccharides in Various Animal Species-extrapolation to Humans", BLOOD COAGULATION & FIBRINOLYSIS, vol. 8, no. 3, 1 January 1997 (1997-01-01), pages 161 - 167, XP001070290, ISSN: 0957-5235, DOI: 10.1097/00001721-199704000-00002
Attorney, Agent or Firm:
BEIJING CHEN QUAN INTELLECTUAL PROPERTY LAW FIRM (CN)
Download PDF: