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Title:
ANTIDEPRESSANT COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/121770
Kind Code:
A1
Abstract:
An antidepressant steroid compound and a preparation method and an application thereof; the structure of said compound is shown in formula (I), and the definition of each substituent is as described in the description and claims. The compound of the present invention may be used in the prevention, treatment, therapy or alleviation of a plurality of diseases and conditions such as depression.

Inventors:
HUANG CHENGGANG (CN)
LI YANG (CN)
JIANG HUALIANG (CN)
XIE YANG (CN)
GUO FEI (CN)
LI ZHIXIONG (CN)
CHEN MINGCANG (CN)
ZHENG MINGYUE (CN)
SUN ZHAOLIN (CN)
GAO YU (CN)
TIAN XIAOTING (CN)
HU PEI (CN)
ZHANG BING (CN)
Application Number:
PCT/CN2017/120134
Publication Date:
July 05, 2018
Filing Date:
December 29, 2017
Export Citation:
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Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
C07J71/00; A61K31/58; A61P3/10; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P31/04; A61P35/00; A61P35/04
Domestic Patent References:
WO2015163318A12015-10-29
WO2005051381A12005-06-09
WO2005051380A12005-06-09
Foreign References:
CN102924559A2013-02-13
CN101031296A2007-09-05
CN101959876A2011-01-26
CN1642558A2005-07-20
CN1452630A2003-10-29
CN101768202A2010-07-07
CN1377367A2002-10-30
CN101214253A2008-07-09
Other References:
TRADITIONAL CHINESE DRUG RESEARCH AND CLINICAL PHARMACOLOGY, vol. 18, 2007, pages 29
BIOL. PHARM. BULL., vol. 29, 2006, pages 2304 - 2306
JOURNAL OF PHARMACEUTICAL PRACTICE, vol. 28, 2010, pages 283 - 287
SAMBROOK ET AL.: "Molecular Cloning: Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
ACTA PHARMACOLOGICA SINICA, vol. 35, no. 9, 2014, pages 1188 - 1198
See also references of EP 3564253A4
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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