Title:
ANTIDEPRESSANT INDOLETETRAHYDROPYRIDINE DERIVATIVES OF 2,3-DIHYDRO-7H-[1,4]DIOXINO[2,3-e]INDOLE
Document Type and Number:
WIPO Patent Application WO2002088146
Kind Code:
A3
Abstract:
Compounds of the formula (I) are useful in the treatment of central nervous system disorders including depression, obsessive compulsive disorder, panic attacks, generalized anxiety disorder, sexual dysfunction, eating disorders and addictive disorders caused by ethanol or cocaine abuse.
Inventors:
STACK GARY PAUL
TRAN MEGAN
BRAVO BYRON ABEL
TRAN MEGAN
BRAVO BYRON ABEL
Application Number:
PCT/US2002/013118
Publication Date:
February 13, 2003
Filing Date:
April 25, 2002
Export Citation:
Assignee:
WYETH CORP (US)
International Classes:
A61K31/407; A61K31/4439; A61P3/04; A61P9/02; A61P15/10; A61P25/00; A61P25/22; A61P25/24; A61P25/32; C07B53/00; C07D491/056; C07D491/04; C07D519/00; (IPC1-7): C07D519/00; C07D491/04; A61K31/407; A61P25/00
Domestic Patent References:
| WO1991013872A1 | 1991-09-19 | |||
| WO1997023485A1 | 1997-07-03 | |||
| WO1998040386A1 | 1998-09-17 |
Other References:
ENNIS M D ET AL: "NOVEL INDOLODIOXANES WITH ANTIHYPERTENSIVE EFFECTS: POTENT LIGANDS FOR THE 5-HT1A RECEPTOR", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 35, no. 16, 7 August 1992 (1992-08-07), pages 3058 - 3066, XP000608326, ISSN: 0022-2623
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