Title:
ANTIGEN-BINDING FUSION PROTEINS WITH MODIFIED HSP70 DOMAINS
Document Type and Number:
WIPO Patent Application WO/2017/156461
Kind Code:
A3
Abstract:
The invention relates to fusion proteins comprising an antigen binding domain fused with a modified heat shock 70 protein. The invention further relates to methods of using the fusion proteins to induce an immune response to antigens and to treat diseases associated with antigens.
Inventors:
BRAUNS TIMOTHY (US)
POZNANSKY MARK C (US)
GELFAND JEFFREY A (US)
CHEN HUABIAO (US)
MCCORMACK STEPHEN J (US)
POZNANSKY MARK C (US)
GELFAND JEFFREY A (US)
CHEN HUABIAO (US)
MCCORMACK STEPHEN J (US)
Application Number:
PCT/US2017/021911
Publication Date:
October 05, 2017
Filing Date:
March 10, 2017
Export Citation:
Assignee:
APERISYS INC (US)
MASSACHUSETTS GEN HOSPITAL (US)
MASSACHUSETTS GEN HOSPITAL (US)
International Classes:
A61K39/04; A61K39/12; A61K39/395; C07K14/35; C07K16/28; C12N1/21; C12N15/09; C12N15/63; C12N15/70
Foreign References:
| US20090068184A1 | 2009-03-12 | |||
| US7932055B2 | 2011-04-26 | |||
| US20140301993A1 | 2014-10-09 | |||
| US8435494B2 | 2013-05-07 | |||
| US20080085539A1 | 2008-04-10 |
Other References:
See also references of EP 3426289A4
Attorney, Agent or Firm:
BONNEN, Alice, M. (US)
Download PDF: