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Title:
ANTIGEN INDUCERS, VACCINE PRECURSORS, VACCINES, ANTIBODIES, NEUTRALIZING ANTIBODIES, ANTITOXINS, IDIOTYPIC ANTIBODIES, AND ANTI-IDIOTYPIC ANTIBODIES INDUCED BY THE IDIOTYPIC ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/1998/032431
Kind Code:
A1
Abstract:
Antigen inducers producing vaccine precursors having high selectivity and specificity, vaccines, antibodies including idiotypic antibodies, neutralizing antibodies, and antitoxins. These inducers, which typically have the fundamental molecular structure represented by the general formula (3-a), induce the non-functional properties of complex high molecular-weight substances forming living organisms and nonliving matters into fundamental structural substances close to the expression of the functions as far as possible by regulating quantum thermodynamically and stoichiometrically expressed functions and morphogenesis of molecules to thereby produce vaccine precursors having high selectivity and specificity, vaccines, antibodies including idiotypic antibodies, neutralizing antibodies and antitoxins. Moreover, use is made of these substances in producing antibacterial agents, antiviral agents, neutralizing antibodies, antitoxins, anticancer agents, antiprotozoal agents against $i(Plasmodium), $i(Spirochaeta), etc., molecular discriminators, histocompatibility enhancers, immune response promoters or immune response regulators serving as labels for antibodies, tissues and organs, and complement chain reaction promoters.

Inventors:
KOYAMA SHOZO (JP)
TANAKA SATOSHI (JP)
Application Number:
PCT/JP1998/000351
Publication Date:
July 30, 1998
Filing Date:
January 28, 1998
Export Citation:
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Assignee:
KOYAMA SHOZO (JP)
TANAKA SATOSHI (JP)
International Classes:
A61K31/12; A61K31/122; A61K39/39; A61K39/395; C12N5/08; C12P21/08; A61K39/00; (IPC1-7): A61K31/12; A61K39/00; A61K39/395; C07K16/00; C07K16/42; C12N5/06; C12N5/08
Domestic Patent References:
WO1996007403A11996-03-14
WO1997001633A11997-01-16
Foreign References:
JPH09221421A1997-08-26
Other References:
KOYAMA S. et al., "Apoptosis-Like (Possible Quantum Thermodynamic) Cell Death Induced by Yoshixol and Wood Oil of Chamaecyparis Obtusa (Kiso-Hinoki) on HeLa Cell", Vol. 28, No. 5, (May 1997), p. 805-811.
KOYAMA S. et al., "A New Substance (Yoshixol) with an Interesting Antibiotic Mechanism from Wood Oil of Japanese Traditional Tree (Kiso-Hinoki), Chamaecyparis Obtusa", Vol. 28, No. 5, (May 1997), p. 797-804.
Attorney, Agent or Firm:
Amino, Makoto (3F 7, Rokubanch, Chiyoda-ku Tokyo 102, JP)
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