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Title:
ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO/2010/055474
Kind Code:
A3
Abstract:
Disclosed are antimicrobial compounds and compositions, the use of such compounds and compositions in the treatment of an infection by microbes and methods for treating an infection by microbes, for example of fungi and oomycetes.

Inventors:
GELLERMAN GARY (IL)
YARDEN ODED (IL)
AIZIKOVICH ALEX (IL)
Application Number:
PCT/IB2009/055016
Publication Date:
December 16, 2010
Filing Date:
November 11, 2009
Export Citation:
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Assignee:
UNIV ARIEL RES & DEV CO LTD (IL)
YISSUM RES DEV CO (IL)
GELLERMAN GARY (IL)
YARDEN ODED (IL)
AIZIKOVICH ALEX (IL)
International Classes:
A61K31/135; A61K31/137; A61K31/275; A61P31/10
Domestic Patent References:
WO2001085673A12001-11-15
WO2007100295A12007-09-07
Other References:
HORSFALL, JAMES G. ET AL: "The effect of synthetic compounds on sporulation of Monilinia fructicola", TRANSACTIONS OF THE NEW YORK ACADEMY OF SCIENCES, CODEN: TNYAAE, vol. 18, 1955, pages 69 - 80, XP002590890, ISSN: 0028-7113
SOSNOVSKIKH, V. YA. ET AL: "Reactions of aromatic and heteroaromatic .beta.-amino-.beta.-(polyfluoroalkyl)vinyl ketones with ethylenediamine. A new synthesis of N,N'-unsubstituted imidazolidines", RUSSIAN CHEMICAL BULLETIN (TRANSLATION OF IZVESTIYA AKADEMII NAUK, SERIYA KHIMICHESKAYA), CODEN: RCBUEY, vol. 48, no. 3, 1999, pages 540 - 551, XP002590891, ISSN: 1066-5285
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; May 1999 (1999-05-01), MATAMOROS-LEÓN B ET AL: "Individual and combined effects of vanillin and potassium sorbate on Penicillium digitatum, Penicillium glabrum, and Penicillium italicum growth.", XP002590892, Database accession no. NLM10340678
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; July 2006 (2006-07-01), NGARMSAK MANATCHAYA ET AL: "Antimicrobial activity of vanillin against spoilage microorganisms in stored fresh-cut mangoes.", XP002590893, Database accession no. NLM16865911
GELLERMAN, GARY ET AL: "Synthesis and antifungal activity of .beta.-trifluoroalkyl aminovinyl ketone derivatives", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, CODEN: JAFCAU, vol. 57, no. 18, 2009, pages 8303 - 8307, XP002590894, ISSN: 0021-8561
Attorney, Agent or Firm:
GUR, Erez (Kfar Saba, IL)
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