Title:
ANTIMICROBIAL SILICONE RUBBER, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/219035
Kind Code:
A1
Abstract:
Disclosed is an antimicrobial silicone rubber, functional macromolecules being chemically bonded to the surface of the silicone rubber and containing vinyl or ethynyl, and the functional macromolecules being chemically bonded to the surface of the silicone rubber by means of vinyl or ethynyl; the functional macromolecules comprise polyamino acid macromolecules of which the molecular structure is as shown in (I) and (II). The antimicrobial silicone rubber of the present invention has polyamino acid macromolecules chemically bonded to the surface of the silicone rubber and serves an antimicrobial function by means of the interaction of polyamino acid macromolecules with a negatively charged cell membrane in bacteria, providing a persistent antimicrobial effect and unlikely causing bacteria to develop any drug resistance; moreover, polyamino acid macromolecules bind to the surface of the silicone rubber by means of chemical bonding, preventing macromolecules from being precipitated and entering a cell, providing good biocompatibility.
Inventors:
NIU ZHIMENG (CN)
ZHANG SHANYONG (CN)
ZHANG SHANYONG (CN)
Application Number:
PCT/CN2018/081292
Publication Date:
December 06, 2018
Filing Date:
March 30, 2018
Export Citation:
Assignee:
SUZHOU DOBIOM MEDICAL TECH CO LTD (CN)
International Classes:
A61K8/898; C08J7/16; A61L15/26
Foreign References:
| CN107141502A | 2017-09-08 | |||
| CN104721875A | 2015-06-24 | |||
| CN101987887A | 2011-03-23 | |||
| CN102028973A | 2011-04-27 | |||
| US20150005457A1 | 2015-01-01 | |||
| KR20010044838A | 2001-06-05 | |||
| CN201558397U | 2010-08-25 | |||
| CN201431691Y | 2010-03-31 | |||
| CN2778285Y | 2006-05-10 | |||
| CN101912638A | 2010-12-15 |
Other References:
See also references of EP 3584277A4
Attorney, Agent or Firm:
BEIJING JWT INTELLECTUAL PROPERTY CO., LTD. (CN)
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