Title:
ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES
Document Type and Number:
WIPO Patent Application WO2001002380
Kind Code:
A8
Abstract:
The invention concerns antipsychotic compounds of formula (I) wherein: A represents a group selected among the following: -CC-; -CH=CH-; -CH2-CH2-; n is equal to 1 or 2; X represents a hydrogen, chlorine or fluorine atom, a methyl or methoxy group; Y represents a hydrogen atom or a chlorine or a fluorine atom; R1 represents a cyclohexyl, phenyl, cycloheptyl, tertiary butyl, dicyclopropylmethyl, bicyclo[3.2.1]octanyl, 4-tetrahydropyranyl, 4-tetrahydrothiopyranyl or adamantyle group; R2 and R3 form together with the nitrogen atom whereto they re bound a cyclic amine; and the additive salts of said compounds with pharmaceutically acceptable acids, as well as their solvates and hydrates.
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Inventors:
BOIGEGRAIN ROBERT (FR)
BOURRIE MARTINE (FR)
LAIR PIERRE (FR)
PAUL RAYMOND (FR)
PONCELET MARTINE (FR)
VERNIERES JEAN-CLAUDE (FR)
BOURRIE MARTINE (FR)
LAIR PIERRE (FR)
PAUL RAYMOND (FR)
PONCELET MARTINE (FR)
VERNIERES JEAN-CLAUDE (FR)
Application Number:
PCT/FR2000/001790
Publication Date:
June 28, 2001
Filing Date:
June 27, 2000
Export Citation:
Assignee:
SANOFI SYNTHELABO (FR)
BOIGEGRAIN ROBERT (FR)
BOURRIE MARTINE (FR)
LAIR PIERRE (FR)
PAUL RAYMOND (FR)
PONCELET MARTINE (FR)
VERNIERES JEAN CLAUDE (FR)
BOIGEGRAIN ROBERT (FR)
BOURRIE MARTINE (FR)
LAIR PIERRE (FR)
PAUL RAYMOND (FR)
PONCELET MARTINE (FR)
VERNIERES JEAN CLAUDE (FR)
International Classes:
A61K31/395; A61K31/4453; A61K31/55; A61P25/00; A61P25/18; C07D295/02; A61P43/00; C07B61/00; C07D295/03; C07D295/06; C07D295/073; C07D295/08; C07D295/096; (IPC1-7): C07D295/06; C07D295/02; C07D295/08; A61K31/55; A61P25/00
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