Title:
ANTITHROMBOTIC MEDICAL MATERIAL USING NICKEL TITANIUM ALLOY
Document Type and Number:
WIPO Patent Application WO/2019/065947
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a medical material using a nickel titanium alloy which reduces the thickness of a polymer electrolyte while supporting an antithrombotic compound in an amount sufficient to create a therapeutic effect. The present invention provides a medical material wherein a nickel titanium alloy has a porous surface and allows a polymer electrolyte to infiltrate the pores, thereby reducing the thickness of the polymer electrolyte exposed at the surface of the nickel titanium alloy and supporting a sufficient amount of an antithrombotic compound as a result of the contribution of the infiltrated polymer electrolyte.
Inventors:
KAKIYAMA SO (JP)
KADOWAKI KOJI (JP)
TANAHASHI KAZUHIRO (JP)
KADOWAKI KOJI (JP)
TANAHASHI KAZUHIRO (JP)
Application Number:
PCT/JP2018/036201
Publication Date:
April 04, 2019
Filing Date:
September 28, 2018
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61L33/10; A61K31/343; A61K31/4164; A61K31/7076; A61K31/727; A61K31/737; A61K31/795; A61K38/05; A61K47/58; A61K47/59; A61K47/61; A61K47/62; A61L27/06; A61L27/16; A61L27/18; A61L27/20; A61L27/22; A61L27/28; A61L27/34; A61L27/42; A61L27/54; A61L27/56; A61L31/02; A61L31/04; A61L31/06; A61L31/08; A61L31/10; A61L31/12; A61L31/14; A61L31/16; A61L33/04; A61L33/06; A61L33/08; A61L33/14; A61P7/02; A61P9/10; A61K47/02
Domestic Patent References:
| WO2015080176A1 | 2015-06-04 | |||
| WO2016190407A1 | 2016-12-01 | |||
| WO2016159243A1 | 2016-10-06 | |||
| WO2007018189A1 | 2007-02-15 | |||
| WO2014136567A1 | 2014-09-12 | |||
| WO2016159243A1 | 2016-10-06 |
Foreign References:
| JP2017000744A | 2017-01-05 | |||
| JP4273965B2 | 2009-06-03 | |||
| JP2011200700A | 2011-10-13 | |||
| JPH10295823A | 1998-11-10 | |||
| JP2002035109A | 2002-02-05 |
Other References:
FIRSTOV, G.S. ET AL.: "Surface oxidation of NiTi shape memory alloy", BIOMATERIALS, vol. 23, 2002, pages 4863 - 4871, XP004380889, ISSN: 0142-9612, DOI: doi:10.1016/S0142-9612(02)00244-2
C. L. CHU ET AL., SCRIPTA MATERIALIA, vol. 52, 2005, pages 1117 - 1121
H. KOMIYAMA ET AL., WORLD JOURNAL OF CARDIOLOGY, vol. 7, 2015, pages 776 - 783
See also references of EP 3689354A4
C. L. CHU ET AL., SCRIPTA MATERIALIA, vol. 52, 2005, pages 1117 - 1121
H. KOMIYAMA ET AL., WORLD JOURNAL OF CARDIOLOGY, vol. 7, 2015, pages 776 - 783
See also references of EP 3689354A4
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