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Title:
ANTITHROMBOTIC MEDICAL MATERIAL
Document Type and Number:
WIPO Patent Application WO/1998/057679
Kind Code:
A1
Abstract:
Antithrombic medical material having on its surface a film made from a graft copolymer produced by grafting a quaternary ammonium monomer and a hydrophilic monomer onto a hydrophobic polymer, characterized in that an anticoagulant such as heparin is immobilized therein in a depth of at least 45 % from the film surface and that the thickness of the film in which the anticoagulant is immobilized is at least 3 $g(m)m. This material has excellent antithrombotic properties and a uniform quality and, particularly, the film is free from discoloration.

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Inventors:
OYAMA YOSHIHIRO (JP)
INOUE SATORU (JP)
Application Number:
PCT/JP1998/002626
Publication Date:
December 23, 1998
Filing Date:
June 15, 1998
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
OYAMA YOSHIHIRO (JP)
INOUE SATORU (JP)
International Classes:
A61L33/10; A61L33/00; (IPC1-7): A61L33/00
Foreign References:
JPS51194A1976-01-05
JPS5714358A1982-01-25
JPH0280056A1990-03-20
JPH02234765A1990-09-17
JPS50143873A1975-11-19
JPS54147696A1979-11-19
JPS63119773A1988-05-24
JPS63119774A1988-05-24
JPH02144070A1990-06-01
JPH05184665A1993-07-27
Other References:
See also references of EP 0956870A4
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