ANTIVIRAL COMPOUND AND PREPARATION METHOD THEREFOR

WIPO Patent Application WO/2022/142731

A1

Disclosed are an antiviral compound and a preparation method therefor. The structural formula of the compound is as represented by formula I. In formula (I), R1 is selected from: monosubstituted or polysubstituted H, F, methyl, and trifluoromethyl; R2 is selected from: H and straight-chain or substituted alkanes (C1-C6); R3 is selected from: monosubstituted or polysubstituted H, Cl, Br, and F. Experiments prove that the compound of the present invention not only has a good inhibition effect on H1N1 influenza A virus, but also has a good inhibition effect on coronavirus. No toxicity to human normal cells is observed, and the degree of an inflammatory response can be inhibited while resisting viruses.

WANG WEI (CN)
LU YONGZHANG (CN)
TAN JINHUI (CN)

PCT/CN2021/128948

July 07, 2022

November 05, 2021

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GUANGDONG ZHONGKE MEDICINE R&D LTD (CN)

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