Title:
ANTIVIRAL PEPTIDES EFFECTIVE AGAINST HEPATITIS C VIRUS
Document Type and Number:
WIPO Patent Application WO/2013/036622
Kind Code:
A3
Abstract:
In certain embodiments this invention provides novel antiviral peptide(s) that are effective against positive sense RNA viruses that have an internal ribosome entry site (IRES). The peptide(s) can be used to inhibit propagation of such viruses and thereby provide a effective modality for the treatment of infections such as hepatitis C, and the like.
Inventors:
FRENCH SAMUEL WHEELER (US)
KHACHATOORIAN RONIK (US)
RUCHALA PIOTR PAWEL (US)
KHACHATOORIAN RONIK (US)
RUCHALA PIOTR PAWEL (US)
Application Number:
PCT/US2012/053936
Publication Date:
May 02, 2013
Filing Date:
September 06, 2012
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
FRENCH SAMUEL WHEELER (US)
KHACHATOORIAN RONIK (US)
RUCHALA PIOTR PAWEL (US)
FRENCH SAMUEL WHEELER (US)
KHACHATOORIAN RONIK (US)
RUCHALA PIOTR PAWEL (US)
International Classes:
A61K38/08; A61K38/10; A61K38/16; A61K38/17; A61P31/00; A61P31/12
Domestic Patent References:
| WO2009067191A2 | 2009-05-28 |
Foreign References:
| US20110091966A1 | 2011-04-21 | |||
| US6291637B1 | 2001-09-18 |
Other References:
KHACHATOORIAN ET AL.: "A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production", HEPATOLOGY, vol. 55, no. 6, 30 January 2012 (2012-01-30), pages 1662 - 1672, XP055066144
Attorney, Agent or Firm:
HUNTER, Tom et al. (P.O. Box 70250Oakland, California, US)
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