Title:
APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
Document Type and Number:
WIPO Patent Application WO/2010/083441
Kind Code:
A3
Abstract:
Disclosed are compounds of formula (I) which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Inventors:
HEXAMER LAURA (US)
DING HONG (US)
ELMORE STEVEN W (US)
KUNZER AARON R (US)
SONG XIAOHONG (US)
SOUERS ANDREW J (US)
SULLIVAN GERARD M (US)
TAO ZHI-FU (US)
WENDT MICHAEL D (US)
DING HONG (US)
ELMORE STEVEN W (US)
KUNZER AARON R (US)
SONG XIAOHONG (US)
SOUERS ANDREW J (US)
SULLIVAN GERARD M (US)
TAO ZHI-FU (US)
WENDT MICHAEL D (US)
Application Number:
PCT/US2010/021243
Publication Date:
September 10, 2010
Filing Date:
January 15, 2010
Export Citation:
Assignee:
ABBOTT LAB (US)
HEXAMER LAURA (US)
DING HONG (US)
ELMORE STEVEN W (US)
KUNZER AARON R (US)
SONG XIAOHONG (US)
SOUERS ANDREW J (US)
SULLIVAN GERARD M (US)
TAO ZHI-FU (US)
WENDT MICHAEL D (US)
HEXAMER LAURA (US)
DING HONG (US)
ELMORE STEVEN W (US)
KUNZER AARON R (US)
SONG XIAOHONG (US)
SOUERS ANDREW J (US)
SULLIVAN GERARD M (US)
TAO ZHI-FU (US)
WENDT MICHAEL D (US)
International Classes:
C07D209/08; A61K31/635; A61P35/00; C07D213/71; C07D231/56; C07D235/04; C07D265/02; C07D285/14; C07D295/155; C07D311/14
Domestic Patent References:
| WO2008024337A2 | 2008-02-28 |
Foreign References:
| US20070072860A1 | 2007-03-29 |
Attorney, Agent or Firm:
MUELLER, Lisa, V. (700 W 47th STSte 100, Kansas City MO, US)
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