Title:
APORPHINE AND SECOAPORPHINE COMPOUNDS FOR TREATMENT OF DIABETES
Document Type and Number:
WIPO Patent Application WO/2006/136063
Kind Code:
A1
Abstract:
The present invention discloses a new type of aporphine or secoaporphine compounds, a process for producing the same, and a pharmaceutical composition comprising the said compound which is used for preventing or treating diabetes. The said composition comprises at least an effective amount of compounds of formula I-IV and medically acceptable carriers and excipient.
Inventors:
LEE SHOEI-SHENG (CN)
SU MING-JAI (CN)
SU MING-JAI (CN)
Application Number:
PCT/CN2005/001311
Publication Date:
December 28, 2006
Filing Date:
August 22, 2005
Export Citation:
Assignee:
LOTUS PHARMACEUTICAL CO LTD (CN)
LEE SHOEI-SHENG (CN)
SU MING-JAI (CN)
LEE SHOEI-SHENG (CN)
SU MING-JAI (CN)
International Classes:
C07D221/18; A61K31/135; A61P3/06; C07C217/66
Foreign References:
| CN1103863A | 1995-06-21 | |||
| US4309542A | 1982-01-05 | |||
| US4188495A | 1980-02-12 |
Other References:
LEE S.-S. ET AL.: "Preparation of phenanthrene alkaloids via solvolysis of 2-hydroxyaporphines", TETRAHEDRON LETTERS, vol. 36, no. 9, 1995, pages 1531 - 1532, XP004028620
LEE S.-S. ET AL.: "A facile semisynthesis of litebamine, a novel phenanthrene alkaloid, from boldine via a biogenetical approach", TETRAHEDRON LETTERS, vol. 33, no. 42, 1992, pages 6309 - 6310, XP003005369
LEE S.-S. ET AL.: "A facile semisynthesis of litebamine, a novel phenanthrene alkaloid, from boldine via a biogenetical approach", TETRAHEDRON LETTERS, vol. 33, no. 42, 1992, pages 6309 - 6310, XP003005369
Attorney, Agent or Firm:
LUNG TIN INTERNATIONAL INTELLECTUAL PROPERTY AGENT LTD. (Tower B Grand Place, No. 5, Huizhong Roa, Chaoyang District Beijing 1, CN)
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