Title:
AN APPARATUS AND METHOD FOR CEREBRAL MICRODIALYSIS TO TREAT NEUROLOGICAL DISEASE, INCLUDING ALZHEIMER'S, PARKINSON'S OR MULTIPLE SCLEROSIS
Document Type and Number:
WIPO Patent Application WO/2017/117138
Kind Code:
A8
Abstract:
An apparatus for performing cerebral micro-dialysis to treat neurological disease of a patient's brain includes a catheter for implantation in or near the patient's brain, an implantable pump communicated with the catheter to transport cerebrospinal fluid (CSF) from the patient, which CSF contains diseased cells or biomolecules associated with the neurological disease, and an implantable separation device communicated with the pump wherein the diseased cells or biomolecules are removed, where the separation apparatus includes a dialysis membrane impregnated with an antibody, a reversible electrostatic filter, and/or a magnetic field effect fractionation chamber wherein a magnetically-tagged antibody scavenges and aids in the removal of circulating diseased cells or biomolecules from the CSF.
Inventors:
CHEN THOMAS (US)
SHACHAR YEHOSHUA (US)
KORNBERG ROGER (US)
SHACHAR YEHOSHUA (US)
KORNBERG ROGER (US)
Application Number:
PCT/US2016/068725
Publication Date:
September 14, 2017
Filing Date:
December 27, 2016
Export Citation:
Assignee:
COGNOS THERAPEUTICS INC (US)
International Classes:
A61M1/14; A61K39/395; A61P25/28; G01N33/53
Attorney, Agent or Firm:
DAWES, Daniel et al. (US)
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