Title:
APPARATUS AND METHOD FOR MULTIPLEXED ROTATING IMAGING BIOASSAYS
Document Type and Number:
WIPO Patent Application WO/2018/045978
Kind Code:
A1
Abstract:
Systems and method for versatile multiplexed spinning/rotating bioassays are provided. This bioassay platform can take the advantage of the high-speed spinning motion, which naturally provides on-the-fly cellular imaging at the rate that cannot be reached by the conventional cameras or laser-scanning techniques, but ultrafast imaging modalities. More importantly, the functionalized solid substrates derived from the disk substrate can be compatible with adherent cell culture as well as biochemically-specific cell-capture, which can now be assayed with ultrafast imaging modalities at an ultra-high-speed line-scan rate of ＞10 MHz. Large-format spinning high-throughput imaging assay could thus be a potent tool for scaling both the assay throughput as well as content/multiplexity as demanded in many applications, e.g. drug discovery, and rare cancer cell screening.
Inventors:
TSIA KIN MAN KEVIN (CN)
TANG HIN LONG (CN)
LAU KAM SENG (CN)
TANG HIN LONG (CN)
LAU KAM SENG (CN)
Application Number:
PCT/CN2017/100841
Publication Date:
March 15, 2018
Filing Date:
September 07, 2017
Export Citation:
Assignee:
VERSITECH LTD (CN)
International Classes:
G01N35/00
Foreign References:
| US20030113925A1 | 2003-06-19 | |||
| US20050002827A1 | 2005-01-06 | |||
| CN101166834A | 2008-04-23 | |||
| CN102301269A | 2011-12-28 | |||
| US20060078935A1 | 2006-04-13 | |||
| US4665553A | 1987-05-12 |
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
Download PDF: