Title:
APPARATUS AND METHOD FOR NANOMANIPULATION OF BIOMOLECULES AND LIVING CELLS
Document Type and Number:
WIPO Patent Application WO2006039675
Kind Code:
A3
Abstract:
The present invention relates to an electromagnetic needle for magnetically manipulating microscopic particles and a method of making the same, and more particularly, to a method for nanomanipulating biomolecules and/or living cells using the electromagnetic needle of the present invention. The temperature-controlled electromagnetic microneedle includes an electromagnetic core having a magnetic probe tip. A wire coil is wound around at least a portion of the core and electrically isolated from the core. A thermo-regulating water jacket having a first and second end and enveloping the electromagnetic core and wire coil allows the probe tip to extend from the first end. Magnetically responsive particles upon which a biologically active substance is absorbed are administered to a subject. A catheter having a magnet attached thereto is inserted into the body of the subject. The magnet guides the particles to a site to be treated with the biologically active substance.
Inventors:
INGBER DONALD E (US)
MATTHEWS BENJAMIN D (US)
LAVAN DAVID A (US)
OVERBY DARRYL (US)
MATTHEWS BENJAMIN D (US)
LAVAN DAVID A (US)
OVERBY DARRYL (US)
Application Number:
PCT/US2005/035551
Publication Date:
June 29, 2006
Filing Date:
October 03, 2005
Export Citation:
Assignee:
CHILDRENS MEDICAL CENTER (US)
INGBER DONALD E (US)
MATTHEWS BENJAMIN D (US)
LAVAN DAVID A (US)
OVERBY DARRYL (US)
INGBER DONALD E (US)
MATTHEWS BENJAMIN D (US)
LAVAN DAVID A (US)
OVERBY DARRYL (US)
International Classes:
A61N2/00
Foreign References:
US20030187320A1 | 2003-10-02 | |||
US6692490B1 | 2004-02-17 | |||
US20040143213A1 | 2004-07-22 | |||
US20030083646A1 | 2003-05-01 | |||
US6673104B2 | 2004-01-06 | |||
US6626819B2 | 2003-09-30 | |||
US6603994B2 | 2003-08-05 |
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