Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
AN APPARATUS FOR MICROFLUIDIC FLOW CYTOMETRY ANALYSIS OF A PARTICULATE CONTAINING FLUID
Document Type and Number:
WIPO Patent Application WO/2017/202932
Kind Code:
A3
Abstract:
An apparatus for microfluidic flow cytometry analysis of a particulate containing fluid An apparatus for microfluidic flow cytometry analysis of a particulate containing fluid comprises a hydrodynamic focussing apparatus for providing a focused stream of particulate containing fluid; and a microfluidic chip. The chip has a plurality of layers and comprises a microfluidic channel that extends through the chip substantially orthogonal to a plane of the layers of the chip, and is in fluid communication with the hydrodynamic focusing apparatus for receipt of a focused steam of particulate containing fluid. The chip also comprises a detection zone comprising at least one pair of electrodes in electrical communication with the microfluidic channel. At least one pair of electrodes comprise an excitation electrode coupled to an AC signal source and a detection electrode configured to detect AC impedance changes in the microfluidic channel between the electrodes resulting from particles passing between the electrodes in the microfluidic channel. Methods of sorting mammalian sperm cells according to sex is also described.

Inventors:
KASHANIN DMITRY (IE)
SHVETS IGOR (IE)
DICORATO FRANCESCO (IE)
Application Number:
PCT/EP2017/062574
Publication Date:
February 22, 2018
Filing Date:
May 24, 2017
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
CELLIX LTD (IE)
International Classes:
G01N35/00; B01L3/00; G01N15/10; G01N15/14; G01N33/487; G01N33/49
Domestic Patent References:
WO2006037561A12006-04-13
WO2015009284A12015-01-22
Foreign References:
US20150024373A12015-01-22
US20090066936A12009-03-12
EP2995961A12016-03-16
GB2383127A2003-06-18
Other References:
GAWAD S ET AL: "MICROMACHINED IMPEDANCE SPECTROSCOPY FLOW CYTOMETER FOR CELL ANALYSIS AND PARTICLE SIZING", LAB ON A CHIP: MINIATURISATION FOR CHEMISTRY, PHYSICS, BIOLOGY, MATERIALS SCIENCE AND BIOENGINEERING, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 1, 1 January 2001 (2001-01-01), pages 76 - 82, XP008028057, ISSN: 1473-0197, DOI: 10.1039/B103933B
Attorney, Agent or Firm:
PURDY, Hugh Barry (IE)
Download PDF:



 
Previous Patent: AFTER-INSECT BITE DEVICE

Next Patent: SYNTHETIC COMPOUND