Title:
APPLICATION OF ALBIFLORIN AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2018/126673
Kind Code:
A1
Abstract:
An application of albiflorin or a pharmaceutically acceptable salt thereof as an IDO inhibitor; albiflorin or a pharmaceutically acceptable salt thereof serving as an IDO inhibitor can be used for preparing a drug, food, health product, food additive, or nutritional supplement for preventing or treating the pathological characteristic diseases of the tryptophan metabolic pathway mediated by IDO overactivation, said diseases being one or more of cancer, depression, Alzheimer's disease, and Parkinson's disease.
Inventors:
ZHANG ZUOGUANG (CN)
Application Number:
PCT/CN2017/095987
Publication Date:
July 12, 2018
Filing Date:
August 04, 2017
Export Citation:
Assignee:
ZHANG ZUOGUANG (CN)
International Classes:
A61K31/7048; A61P25/16; A61P25/24; A61P25/28; A61P27/12; A61P35/00; A61P37/00
Domestic Patent References:
| WO2012068958A1 | 2012-05-31 |
Foreign References:
| CN103417561A | 2013-12-04 | |||
| CN102125575A | 2011-07-20 | |||
| CN102038701A | 2011-05-04 | |||
| CN103301146A | 2013-09-18 |
Other References:
ZHU, YINGLI ET AL.: "[Comparative study on effects of blood enriching on mouse model of blood deficiency syndrome induced by cyclophosphamide of albiflorin, paeoniflorin on levels of GM-CSF, IL-3 and TNF-α].", CHINA JOURNAL OF CHINESE MATERIA MEDICA, vol. 40, no. 2, 31 January 2015 (2015-01-31), pages 330 - 333, XP9515324
YAN, RONG: "Neuroprotective Effects of Paeoniflor and Albiflorin, Two Major Constituents of JD-30", DOCTORAL DISSERTATION, 15 February 2015 (2015-02-15), pages 1 - 103, XP009515640
See also references of EP 3566707A4
FRIBERG M ET AL., INT J CANCER, vol. 101, 2002, pages 151 - 155
YAN, RONG: "Neuroprotective Effects of Paeoniflor and Albiflorin, Two Major Constituents of JD-30", DOCTORAL DISSERTATION, 15 February 2015 (2015-02-15), pages 1 - 103, XP009515640
See also references of EP 3566707A4
FRIBERG M ET AL., INT J CANCER, vol. 101, 2002, pages 151 - 155
Attorney, Agent or Firm:
PANAWELL & PARTNERS, LLC (CN)
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