Title:
APPLICATION OF COMPOUND IN PREPARATION OF DRUG FOR TREATING MYELOFIBROSIS AND RELATED SYMPTOMS/SIGNS THEREOF, AND USE OF COMPOUND
Document Type and Number:
WIPO Patent Application WO/2022/268075
Kind Code:
A1
Abstract:
The present invention provides an application of a compound in the preparation of drug for treating myelofibrosis and related symptoms/signs thereof, and a use of the compound. The compound is selected from one or more of a compound having a structure as shown in formula I, and a pharmaceutically-acceptable salt, prodrug, solvate, and hydrate thereof.
Inventors:
GUO JING (CN)
YAN DAN (CN)
WANG YU (CN)
XU TONG (CN)
LI KAO (CN)
XU WEI (CN)
LAN HONG (CN)
DING LIEMING (CN)
WANG JIABING (CN)
YAN DAN (CN)
WANG YU (CN)
XU TONG (CN)
LI KAO (CN)
XU WEI (CN)
LAN HONG (CN)
DING LIEMING (CN)
WANG JIABING (CN)
Application Number:
PCT/CN2022/100134
Publication Date:
December 29, 2022
Filing Date:
June 21, 2022
Export Citation:
Assignee:
BETTA PHARMACEUTICALS CO LTD (CN)
International Classes:
A61K31/4985; A61P35/00
Domestic Patent References:
| WO2019120234A2 | 2019-06-27 | |||
| WO2021233371A1 | 2021-11-25 |
Foreign References:
| CN111727189A | 2020-09-29 | |||
| US20210379074A1 | 2021-12-09 |
Other References:
TREMBLAY DOUGLAS, MASCARENHAS JOHN: "Next Generation Therapeutics for the Treatment of Myelofibrosis", CELLS, vol. 10, no. 5, 1 May 2021 (2021-05-01), pages 1034 - 19, XP093017013, ISSN: 2073-4409, DOI: 10.3390/cells10051034
NANGALIA J ET AL., NEJM, vol. 369, no. 25, 2013, pages 2391 - 405
TEFFERI A., AM J HEMATOL, vol. 96, no. 1, January 2021 (2021-01-01), pages 145 - 162
TEFFERI, A.: "JAK inhibitors for myeloproliferative neoplasms: clarifying facts from myths", BLOOD, vol. 119, no. 12, 2012, pages 2721 - 2730
NANGALIA J ET AL., NEJM, vol. 369, no. 25, 2013, pages 2391 - 405
TEFFERI A., AM J HEMATOL, vol. 96, no. 1, January 2021 (2021-01-01), pages 145 - 162
TEFFERI, A.: "JAK inhibitors for myeloproliferative neoplasms: clarifying facts from myths", BLOOD, vol. 119, no. 12, 2012, pages 2721 - 2730
Attorney, Agent or Firm:
KANGXIN PARTNERS, P.C. (CN)
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