Title:
APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2016/119085
Kind Code:
A1
Abstract:
Disclosed is an application of ethyl p-methoxycinnamate and derivatives thereof in preparing drugs, culture media, regulating agents or cosmetics and skin care products for maintaining self-renewal and pluripotency of stem cells. The stem cells comprise adult stem cells, embryonic stem cells and induced pluripotent stem (iPS) cells. Also disclosed is an application of the ethyl p-methoxycinnamate and the derivatives thereof to expansion in vitro of stem cells and preparation of iPS cells and an application of the ethyl p-methoxycinnamate and the derivatives thereof in preparing drugs for treating cell deletion or injury diseases.
Inventors:
BAO YONGLI (CN)
LI YUXIN (CN)
QIN HONGSHUANG (CN)
LI YUXIN (CN)
QIN HONGSHUANG (CN)
Application Number:
PCT/CN2015/000311
Publication Date:
August 04, 2016
Filing Date:
May 05, 2015
Export Citation:
Assignee:
UNIV NORTHEAST NORMAL (CN)
International Classes:
C12N5/074; A61K8/37; A61K31/216; A61P7/00; A61P9/00; A61P17/00; A61P25/00; A61P37/00; A61Q19/00; C12N5/071; C12N5/0735
Domestic Patent References:
| WO2014136519A1 | 2014-09-12 |
Foreign References:
| CN1899280A | 2007-01-24 | |||
| CN101703497A | 2010-05-12 |
Other References:
LIU, YIMING ET AL.: "CAPE Promotes the Expansion of Human Umbilical Cord Blood Derived Hematopoietic Stem and Progenitor Cells in Vitro", SCIENCE CHINA : LIFE SCIENCES, vol. 57, no. 2, 28 February 2014 (2014-02-28), pages 188 - 194
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