Title:
APPLICATION OF MULBERRY EXTRACT IN PREPARATION OF DRUG FOR TREATING ULCERATIVE COLITIS
Document Type and Number:
WIPO Patent Application WO/2023/186181
Kind Code:
A1
Abstract:
Disclosed in the present invention is an application of a mulberry extract. The application is an application of the mulberry extract in the preparation of a product for treating and/or preventing ulcerative colitis. In the present invention, experiments prove that a positive drug group, SZ-A-1, SZ-A-2, SZ-A-3, SZ-A-4 and SZ-A-5 (pretreatment) can all significantly inhibit the atrophy of the colon of a UC model mouse. The effect of SZ-A-2, SZ-A-3 and SZ-A-4 groups is equivalent to that of the positive drug group, and the colon atrophy inhibition effect of SZ-A-5 (pretreatment) is better than that of the positive drug group. The mulberry extract provided by the invention, as a component derived from natural plants, has the unique advantages of having small toxic and side effects, and mild and lasting effects. Therefore, the mulberry extract with greatly improved medication safety has great advantages in treating ulcerative colitis.
Inventors:
LIU YULING (CN)
YE JUN (CN)
LIU DONGDONG (CN)
WANG HONGLIANG (CN)
WANG MO (CN)
LI RENJIE (CN)
YANG YANFANG (CN)
YE JUN (CN)
LIU DONGDONG (CN)
WANG HONGLIANG (CN)
WANG MO (CN)
LI RENJIE (CN)
YANG YANFANG (CN)
Application Number:
PCT/CN2023/093572
Publication Date:
October 05, 2023
Filing Date:
May 11, 2023
Export Citation:
Assignee:
BEIJING WEHAND BIO PHARMACEUTICAL CO LTD (CN)
GUANGXI WEHAND BIO PHARMACEUTICAL CO LTD (CN)
GUANGXI WEHAND BIO PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K36/605; A61P1/00; A61P1/04; A61K127/00; A61K129/00; A61K135/00
Foreign References:
| CN114601865A | 2022-06-10 | |||
| CN104857329A | 2015-08-26 | |||
| CN113143996A | 2021-07-23 | |||
| KR20180042729A | 2018-04-26 | |||
| KR20190125020A | 2019-11-06 |
Other References:
ZHENG SHUN HUA, CUI RU TAO: "Experimental Study on Ulcerative Colitis Treated by "Lung-intestine Nourishing Decoction"", SHANG HAI ZHONG YI YAO ZA ZHI : YUE KAN = SHANGHAI JOURNAL OF TRADITIONAL CHINESE MEDICINE, SHANG HAI ZHONG YI YAO DA XUE; SHANG HAI SHI ZHONG YI YAO XUE HUI ZHU BAN. SHANG HAI ZHONG YI YAO ZA ZHI SHE BIAN JI CHU BAN, CN, no. 06, 15 June 2000 (2000-06-15), CN , pages 10 - 12, XP009549442, ISSN: 1007-1334, DOI: 10.16305/j.1007-1334.2000.06.004
Attorney, Agent or Firm:
JEEKAI & PARTNERS (CN)
Download PDF: