Title:
APPLICATION OF PHARMACEUTICAL COMPOSITION HAVING SPECIFIC DRUG-TO-LIPID RATIO IN ANTITUMOR
Document Type and Number:
WIPO Patent Application WO/2022/242762
Kind Code:
A1
Abstract:
An antitumor chemotherapeutic drug liposome having a low drug-to-lipid ratio and an application thereof. The antitumor chemotherapeutic drug liposome comprises an antitumor drug and a liposome as a carrier, wherein the drug-to-lipid ratio of the antitumor drug to the lipid carrier is between 0.01 and 0.15.
Inventors:
XU YUHONG (CN)
CHEN XIAOLONG (CN)
JIN SHANSHAN (CN)
CHEN XIAOLONG (CN)
JIN SHANSHAN (CN)
Application Number:
PCT/CN2022/094221
Publication Date:
November 24, 2022
Filing Date:
May 20, 2022
Export Citation:
Assignee:
HIGHFIELD BIOPHARMACEUTICALS CORP (CN)
International Classes:
A61K9/127; A61K31/704; A61K47/24; A61K47/28; A61P35/00
Foreign References:
| CN112137958A | 2020-12-29 | |||
| CN101317820A | 2008-12-10 | |||
| CN101264056A | 2008-09-17 | |||
| CN110755611A | 2020-02-07 | |||
| US5616341A | 1997-04-01 |
Other References:
JIANG FENG, JIANG-HAO CHEN, TIE-HONG YANG, LI FAN, YOU-BEI QIAO, HONG WU: "Preparation and Biological Activity in vitro of Trastuzumab-modified Doxorubicin Immunoliposome", PROGRESS IN MODERN BIOMEDICINE, XIAN DAI SHENG WU YI XUE JIN ZHAN BIAN JI BU, CN, vol. 14, no. 21, 30 July 2014 (2014-07-30), CN , pages 4022 - 4028, XP093006257, ISSN: 1673-6273, DOI: 10.13241/j.cnki.pmb.2014.21.006
CANCER CHEMOTHER PHARMACOL, vol. 71, 2013, pages 555 - 564
INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 391, 2010, pages 248 - 259
BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1758, 2006, pages 55 - 64
CANCER CHEMOTHER PHARMACOL, vol. 71, 2013, pages 555 - 564
INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 391, 2010, pages 248 - 259
BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1758, 2006, pages 55 - 64
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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