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Title:
APPLICATIONS OF PINOCEMBRIN IN PREPARING ANTI-CEREBRAL HEMORRHAGE MEDICAMENT
Document Type and Number:
WIPO Patent Application WO/2018/090358
Kind Code:
A1
Abstract:
Applications of pinocembrin in preparing a medicament for treating cerebral hemorrhage. Cerebral hemorrhage comprises transformative hemorrhage after the onset of cerebral embolism and induced by factors such as a thrombolytic medicament. Experiments and research show that pinocembrin can reduce blood exudation in a cerebral infarction area after the onset of cerebral embolism in a rat, effectively reduce hemorrhagic transformation when the thrombolytic medicament is used, and significantly reduce the number of death in rats caused by cerebral hemorrhage. Pinocembrin is applicable in preparing the medicament for treating cerebral hemorrhage, hemorrhagic transformation, and hemorrhage caused by side effects of a thrombolytic agent, mitigates secondary hemorrhage in an ischemic area, and improves the prognosis of a patient.

Inventors:
DU GUANHUA (CN)
MA YINZHONG (CN)
SONG JUNKE (CN)
LI LI (CN)
NIU ZIRAN (CN)
WU SONG (CN)
LV YANG (CN)
Application Number:
PCT/CN2016/106556
Publication Date:
May 24, 2018
Filing Date:
November 21, 2016
Export Citation:
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Assignee:
INST MATERIA MEDICA CAMS (CN)
International Classes:
A61K31/352; A61P7/04
Foreign References:
CN106166147A2016-11-30
CN101744806A2010-06-23
CN1695608A2005-11-16
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