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Title:
AQUEOUS COMPOSITION CONTAINING STABILIZED 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID
Document Type and Number:
WIPO Patent Application WO/2015/046281
Kind Code:
A1
Abstract:
 An aqueous composition containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid or a salt thereof, benzalkonium bromide, and polyoxyethylene sorbitan fatty acid ester wherein the stability of the 2-amino-3-(4-bromobenzoyl)phenylacetic acid in the aqueous composition is improved by limiting the content of benzalkonium bromide and polyoxyethylene sorbitan fatty acid ester to a certain range.

Inventors:
OKAMOTO TOMOYUKI (JP)
YAMAGUCHI MAO (JP)
Application Number:
PCT/JP2014/075342
Publication Date:
April 02, 2015
Filing Date:
September 25, 2014
Export Citation:
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Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K31/196; A61K9/08; A61K47/18; A61K47/34; A61P29/00
Domestic Patent References:
WO2012099142A12012-07-26
WO2004064828A12004-08-05
WO2006049250A12006-05-11
Foreign References:
JP2009161454A2009-07-23
CN101313899A2008-12-03
JP2010509361A2010-03-25
JP2006500328A2006-01-05
JP2012526106A2012-10-25
Other References:
WAKIKO ASAYAMA ET AL.: "Effectivity of bromfenac for antimicrobial activity in bromfenac ophthalmic solution", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 132, no. 4, 5 March 2012 (2012-03-05), pages 314
Attorney, Agent or Firm:
TSUKUNI & ASSOCIATES et al. (JP)
Patent business corporation Tsukuni (JP)
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