Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/105234
Kind Code:
A1
Abstract:
The present invention relates to an aromatic compound, a pharmaceutical composition comprising the compound, and a method for preparing the compound and an intermediate thereof. The present invention further relates to use of the compound in the preparation of a medicament for the prevention or treatment of PPAR-related diseases.

Inventors:
ZHU JIAWANG (CN)
SONG ZHIQUAN (CN)
LONG DONG (CN)
WANG LICHUN (CN)
WANG JINGYI (CN)
Application Number:
PCT/CN2018/115615
Publication Date:
June 06, 2019
Filing Date:
November 15, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07D333/56; A61K31/381; A61K31/47; A61K31/5377; A61P1/16; C07D215/14; C07D215/18; C07D215/227; C07D237/28; C07D401/04; C07D405/12
Foreign References:
US3558612A1971-01-26
Other References:
RAPHAEL STOLL: "Chalcone Derivatives Antagonize Interactions between the Human Oncoprotein MDM2 and p53", BIOCHEMISTRY, vol. 40, no. 2, 13 December 2000 (2000-12-13), pages 336 - 344, XP002262903, ISSN: 1520-4995
HARINADHA BABU V ET AL: "Synthesis and Biological Evaluation of some Novel Pyrazolines", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 69, no. 3, 1 May 2007 (2007-05-01), pages 470 - 473, XP055683614, ISSN: 0250-474X, DOI: 10.4103/0250-474X.34569
R. SUTHAKARAN: "Synthesis, Antiinflammatory, Antioxidant and Antibacterial Activities of 7-Methoxy Benzofuran Pyrazoline Derivatives", ASIAN JOURNAL OF CHEMISTRY, vol. 19, no. 5, 31 December 2007 (2007-12-31), pages 3353 - 3362, XP055617059, ISSN: 0970-7077
AHMED KAMAL: "Synthesis and Anticancer Activity of 4beta -alkylamidocalcone and 4beta -cinnamido Linked Podophyllotoxins as Apoptotic Inducing Agents", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, 20 November 2011 (2011-11-20), pages 530 - 545, XP028442431, ISSN: 0970-7077
STAHLWERMUTH: "Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
T. HIGUCHIV STELLA: "Pro-drugs as Novel Delivery Systems", ACS SYMPOSIUM SERIES, vol. 14, pages 390 - 392
H. BUNDGAARD: "Design of Prodrugs", 1985, ELSEVIER
T.W. GREENEP.G.M. WUTS: "Protective Groups in Organic Synthesis", 2006, WILEY-INTER SCIENCE
SYNTHESIS, vol. 1626, 2003
BIZET ET AL., JOURNAL OF FLUORINE CHEMISTRY, 2013, pages 56 - 61
JOHNSON ET AL., HETEROCYCLES, 2006, pages 2165 - 2170
WANG ET AL., CHEMICAL COMMUNICATIONS, 2016, pages 2811 - 2814
See also references of EP 3719010A4
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
Download PDF: