Title:
AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/184177
Kind Code:
A1
Abstract:
Disclosed in the present invention is an aromatic compound, a preparation method therefor, and an application thereof. The present invention provides a compound as represented by formula I or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits, in an NASH model-based animal experiment, good safety, tolerance, an effect of reducing liver fat of mice, and a potential therapeutic effect of treating NASH.
Inventors:
SHEN XIAOKUN (CN)
LIU HUIXIN (CN)
LIU HUIXIN (CN)
Application Number:
PCT/CN2022/079388
Publication Date:
September 09, 2022
Filing Date:
March 04, 2022
Export Citation:
Assignee:
FUKANG SHANGHAI HEALTH TECH CO LTD (CN)
International Classes:
C07D403/10; A61K31/53; A61P1/16; A61P3/04; A61P5/14; C07D253/02; C07D403/12
Domestic Patent References:
| WO2020073974A1 | 2020-04-16 | |||
| WO2021257804A1 | 2021-12-23 |
Foreign References:
| CN111801324A | 2020-10-20 | |||
| CN112409340A | 2021-02-26 | |||
| CN111592528A | 2020-08-28 | |||
| CN110627773A | 2019-12-31 | |||
| CN109574995A | 2019-04-05 | |||
| CN113454069A | 2021-09-28 |
Other References:
BERGE ET AL.: "Pharmaceutical Salts", JOURNAL OF PHARMACEUTICALSCIENCE, vol. 66, 1977, pages 1 - 19, XP002675560, DOI: 10.1002/jps.2600660104
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
JOURNAL OF HEPATOLOGY, vol. 47, 2007, pages 598 - 607
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
JOURNAL OF HEPATOLOGY, vol. 47, 2007, pages 598 - 607
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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