Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/134641
Kind Code:
A1
Abstract:
An aromatic heterocyclic compound, a pharmaceutical composition and use thereof. Specifically disclosed are a compound as shown in formula I, a stereoisomer thereof, a diastereomer thereof, or a pharmaceutically acceptable salt of any one of the foregoing, or a crystal form or solvate of any one of the foregoing. The aromatic heterocyclic compound has a novel structure, good CDK7 inhibitory activity, and good selectivity.

Inventors:
GU XIAOHUI (CN)
BAI HAIYUN (CN)
BARBEAU OLIVIER RÉMY (GB)
BESNARD JÉRÉMY (GB)
Application Number:
PCT/CN2021/115031
Publication Date:
June 30, 2022
Filing Date:
August 27, 2021
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
GT APEIRON THERAPEUTICS LTD (CN)
International Classes:
C07D401/14; A61K31/495; A61K31/505; A61K31/506; A61P35/00; C07D401/00; C07D413/14; C07D417/14; C07D471/04
Domestic Patent References:
WO2019143719A12019-07-25
WO2019143730A12019-07-25
WO2015058163A22015-04-23
WO2006038001A12006-04-13
WO2020093011A12020-05-07
WO2019143719A12019-07-25
Foreign References:
CN110036004A2019-07-19
US20140031360A12014-01-30
CN202011552478A2020-12-24
CN201780057760A2017-07-13
Other References:
BERGE ET AL.: "Pharmaceutical Salts", JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 66, 1977, pages 1 - 19, XP002675560, DOI: 10.1002/jps.2600660104
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
"Pharmacopoeia of the People's Republic of China", vol. IV, 2015
RAYMOND C ROWE: "Handbook of Pharmaceutical Excipients", 2009
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: CONTROL METHOD, APPARATUS, POWER SYSTEM AND ELECTRIC VEHICLE

Next Patent: AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF