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Title:
AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/004882
Kind Code:
A1
Abstract:
Provided herein are aromatic heterocyclic derivatives or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof used for treating Alzheimer's disease. Also provided herein are pharmaceutical compositions containing such compounds, and use of such compounds or pharmaceutical compositions thereof for managing or treating 5-HT6 receptor-mediated diseases, especially in the manufacture of a medicament for managing or treating Alzheimer's disease.

Inventors:
ZHANG, Yingjun (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
JIN, Chuanfei (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
ZHONG, Wenhe (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
CHEN, Kangzhi (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
GAO, Li (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
LIU, Runzhi (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
ZHANG, Ji (Dongyangguang Hi-tech Park, Zhen An Road No. 368 Shang Sha, Chang An Tow, Dongguan Guangdong 1, 523871, CN)
Application Number:
CN2015/083605
Publication Date:
January 14, 2016
Filing Date:
July 08, 2015
Export Citation:
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Assignee:
SUNSHINE LAKE PHARMA CO., LTD. (Northern Industrial Area, Songshan LakeDongguan, Guangdong 0, 523000, CN)
International Classes:
C07D209/10; A61K31/454; A61K31/496; A61P1/00; A61P3/04; A61P21/00; A61P25/00; C07D209/42; C07D401/04; C07D401/12; C07D405/12
Domestic Patent References:
WO2011016528A12011-02-10
WO2011088836A12011-07-28
Other References:
See also references of EP 3166924A4
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (Room 301, Trade Building Zhaolanyuan, Tsinghua University,Qinghuayuan, Haidian District, Beijing 4, 100084, CN)
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