Title:
AROMATIZATION METHOD FOR NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2023/056714
Kind Code:
A1
Abstract:
The present application relates to an aromatization method for a nitrogen-containing heterocyclic compound. The aromatization method for a nitrogen-containing heterocyclic compound comprises: in a solvent, using a nitrogen-containing heterocyclic compound as a reaction substrate, a transition metal salt or a complex formed by a transition metal salt and an organic compound as a catalyst, and a peroxide as an oxidant, reacting same to obtain a reaction solution containing an aromatization product of the nitrogen-containing heterocyclic compound. The aromatization method for a nitrogen-containing heterocyclic compound provided in the present application has mild reaction conditions, a small catalyst amount, a simple post-treatment process, and high yield and purity of a reaction product, and simple operation.
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Inventors:
ZHAO NA (CN)
ZHANG YAOLIN (CN)
LI ZHIFENG (CN)
ZHAO JIANQIN (CN)
JIA CHENGGUO (CN)
ZHANG YAOLIN (CN)
LI ZHIFENG (CN)
ZHAO JIANQIN (CN)
JIA CHENGGUO (CN)
Application Number:
PCT/CN2021/141348
Publication Date:
April 13, 2023
Filing Date:
December 24, 2021
Export Citation:
Assignee:
HEBEI VEYONG BIO CHEM CO LTD (CN)
International Classes:
C07D209/08; C07B35/04; C07D215/04; C07D249/12
Foreign References:
| CN113788778A | 2021-12-14 | |||
| CN103012238A | 2013-04-03 | |||
| CN111303059A | 2020-06-19 | |||
| CN110467569A | 2019-11-19 | |||
| CN108912062A | 2018-11-30 |
Other References:
SATORU MURATA, MASAHIRO MIURA, MASAKATSU NOMURA: "Oxidation of N-acyl-pyrrolidines and -piperidines with lron(II)-hydrogen peroxide and an iron complex-molecular oxygen", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1, ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, UK, 1 January 1987 (1987-01-01), Cambridge, UK , pages 1259, XP055297105, ISSN: 0300-922X, DOI: 10.1039/p19870001259
BO YU: "Synthesis Process Optimization on Prothioconazole", AGROCHEMICALS, vol. 56, no. 2, 1 February 2017 (2017-02-01), pages 105 - 107, XP093055686
ANANTHNAG GUDDEKOPPA S., ADHIKARI ADITHYA, BALAKRISHNA MARAVANJI S.: "Iron-catalyzed aerobic oxidative aromatization of 1,3,5-trisubstituted pyrazolines", CATALYSIS COMMUNICATIONS, ELSEVIER, AMSTERDAM, NL, vol. 43, 1 January 2014 (2014-01-01), AMSTERDAM, NL , pages 240 - 243, XP093055687, ISSN: 1566-7367, DOI: 10.1016/j.catcom.2013.09.002
SUMIT CHAKRABORTY, WILLIAM W. BRENNESSEL, WILLIAM D. JONES: "A Molecular Iron Catalyst for the Acceptorless Dehydrogenation and Hydrogenation of N-Heterocycles", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 136, no. 24, 18 June 2014 (2014-06-18), pages 8564 - 8567, XP055510803, ISSN: 0002-7863, DOI: 10.1021/ja504523b
BO YU: "Synthesis Process Optimization on Prothioconazole", AGROCHEMICALS, vol. 56, no. 2, 1 February 2017 (2017-02-01), pages 105 - 107, XP093055686
ANANTHNAG GUDDEKOPPA S., ADHIKARI ADITHYA, BALAKRISHNA MARAVANJI S.: "Iron-catalyzed aerobic oxidative aromatization of 1,3,5-trisubstituted pyrazolines", CATALYSIS COMMUNICATIONS, ELSEVIER, AMSTERDAM, NL, vol. 43, 1 January 2014 (2014-01-01), AMSTERDAM, NL , pages 240 - 243, XP093055687, ISSN: 1566-7367, DOI: 10.1016/j.catcom.2013.09.002
SUMIT CHAKRABORTY, WILLIAM W. BRENNESSEL, WILLIAM D. JONES: "A Molecular Iron Catalyst for the Acceptorless Dehydrogenation and Hydrogenation of N-Heterocycles", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 136, no. 24, 18 June 2014 (2014-06-18), pages 8564 - 8567, XP055510803, ISSN: 0002-7863, DOI: 10.1021/ja504523b
Attorney, Agent or Firm:
HEBEI GUOWEIZHIYUAN INTELLECTUAL PROPERTY AGENCY CO.,LTD (CN)
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