Title:
ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS
Document Type and Number:
WIPO Patent Application WO/2017/066562
Kind Code:
A3
Abstract:
The present invention is drawn to artificial metalloenzymes for use in cyclopropanation reactions, amination and C-H insertion.
Inventors:
HARTWIG JOHN F (US)
KEY HANNA M (US)
DYDIO PAWEL (US)
CLARK DOUGLAS S (US)
KEY HANNA M (US)
DYDIO PAWEL (US)
CLARK DOUGLAS S (US)
Application Number:
PCT/US2016/057032
Publication Date:
July 20, 2017
Filing Date:
October 14, 2016
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
International Classes:
C07D207/00; B01J31/28; C07D487/22
Foreign References:
| US20110243849A1 | 2011-10-06 | |||
| US7129329B1 | 2006-10-31 |
Other References:
ANDING ET AL.: "Iridium Porphyrin Catalyzed N-H Insertion Reactions: Scope and Mechanism", ORGANOMETALLICS, vol. 32, 2013, pages 2599 - 2607, XP055398933
HVASANOV ET AL.: "Optimising the synthesis, polymer membrane encapsulation and photoreduction performance of Ru(II)- and Ir(III)-bis(terpyridine) cytochrome c bioconjugates", ORG. BIOMOL. CHEM., vol. 11, 2013, pages 4 602, XP055398935
UNO ET AL.: "Inversion of Axial Coordination in Myoglobin to Create a ''Proximal'' Ligand Binding Pocket", BIOCHEMISTRY, vol. 42, 2003, pages 10191 - 10199, XP055398937
DYDIO ET AL.: "An artificial metalloenzyme with the kinetics of native enzymes", SCIENCE, vol. 354, no. 6308, 7 October 2016 (2016-10-07), pages 102 - 106, XP055398939
HVASANOV ET AL.: "Optimising the synthesis, polymer membrane encapsulation and photoreduction performance of Ru(II)- and Ir(III)-bis(terpyridine) cytochrome c bioconjugates", ORG. BIOMOL. CHEM., vol. 11, 2013, pages 4 602, XP055398935
UNO ET AL.: "Inversion of Axial Coordination in Myoglobin to Create a ''Proximal'' Ligand Binding Pocket", BIOCHEMISTRY, vol. 42, 2003, pages 10191 - 10199, XP055398937
DYDIO ET AL.: "An artificial metalloenzyme with the kinetics of native enzymes", SCIENCE, vol. 354, no. 6308, 7 October 2016 (2016-10-07), pages 102 - 106, XP055398939
Attorney, Agent or Firm:
LOCKYER, Jean M. et al. (US)
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