Title:
ARYL PHOSPHORUS OXIDE DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/253860
Kind Code:
A1
Abstract:
The present invention relates to an aryl phosphorus oxide derivative inhibitor, a preparation method therefor and the use thereof. In particular, the present invention relates to a compound represented by general formula (IA), a preparation method therefor, a pharmaceutical composition containing the compound, and the use of same as an EGFR inhibitor in the treatment of tumor-related diseases.
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Inventors:
GAO PENG (CN)
WANG SHAOBAO (CN)
SUN GUANGJUN (CN)
XIU WENHUA (CN)
TAN SONGLIANG (CN)
CAI JIAQIANG (CN)
BAO RUDI (CN)
WANG SHAOBAO (CN)
SUN GUANGJUN (CN)
XIU WENHUA (CN)
TAN SONGLIANG (CN)
CAI JIAQIANG (CN)
BAO RUDI (CN)
Application Number:
PCT/CN2020/097362
Publication Date:
December 24, 2020
Filing Date:
June 22, 2020
Export Citation:
Assignee:
JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD (CN)
SHANGHAI HANSOH BIOMEDICAL CO LTD (CN)
SHANGHAI HANSOH BIOMEDICAL CO LTD (CN)
International Classes:
C07D401/12; A61K31/505; A61K31/675; A61P35/00
Domestic Patent References:
| WO2019015655A1 | 2019-01-24 | |||
| WO2007120596A1 | 2007-10-25 |
Foreign References:
| CN1882578A | 2006-12-20 | |||
| CN1852900A | 2006-10-25 | |||
| CN1697830A | 2005-11-16 | |||
| CN101730692A | 2010-06-09 | |||
| CN1293665A | 2001-05-02 | |||
| CN103153064A | 2013-06-12 |
Other References:
"RN1824373-78-5", REGISTRY ENTERS STN, 7 December 2015 (2015-12-07), DOI: 20200720101503X
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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