ARYLACETATE DERIVATIVE HAVING ISOXAZOLE SKELETON

Title:

ARYLACETATE DERIVATIVE HAVING ISOXAZOLE SKELETON

Document Type and Number:

WIPO Patent Application WO/2006/126514

Kind Code:

A1

Abstract:

A compound represented by the formula (I), a pharmaceutically acceptable salt of the compound, or a solvate of the compound or salt: (I) wherein Y represents a group represented by the formula (II) below, provided that Y is not a phenyl which is substituted by a group represented by the formula: -CR⁹R¹⁰X³ in para-position and which may have a substituent; R¹ to R¹⁰ independently represent a halogen, a hydroxy, a lower alkyl which may have a substituent, an aryl which may have a substituent or the like; and X¹ represents -O-, -S- or the like: (II) wherein the ring A represents an aryl which may have a substituent or a heteroaryl which may have a substituent; and X³ represents COOR¹⁷ or the like.

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Inventors:

KANDA YASUHIKO (JP)

Application Number:

PCT/JP2006/310198

Publication Date:

November 30, 2006

Filing Date:

May 23, 2006

Export Citation:

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Assignee:

SHIONOGI & CO (JP)
KANDA YASUHIKO (JP)

International Classes:

C07D261/08; A61K31/42; A61K31/4439; A61K31/541; A61P1/04; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P5/16; A61P5/50; A61P9/10; A61P9/12; A61P11/02; A61P13/12; A61P15/08; A61P17/06; A61P19/10; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P37/08; A61P43/00; C07D413/06; C07D413/12

Domestic Patent References:

WO2004091604A1	2004-10-28
WO1999046232A1	1999-09-16
WO2002102780A1	2002-12-27
WO1999011255A1	1999-03-11
WO2005054213A1	2005-06-16
WO2006045554A1	2006-05-04
WO1999011255A1	1999-03-11
WO1999058510A1	1999-11-18
WO2001000603A1	2001-01-04
WO1999046232A1	1999-09-16
WO2004063166A1	2004-07-29
WO2002053547A1	2002-07-11
WO2003099793A1	2003-12-04
WO2004091604A1	2004-10-28

Foreign References:

EP0558062A2

1993-09-01

Other References:

See also references of EP 1887000A4
CURRENT MEDICINAL CHEMISTRY, vol. 10, 2003, pages 267 - 280
J. MED. CHEM., vol. 47, 2004, pages 720 - 725

Attorney, Agent or Firm:

Takayama, Hirotsugu (Intellectual Property Department, 12-4, Sagisu 5-chome, Fukushima-k, Osaka-shi Osaka 02, JP)

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