Title:
ARYLSULFONYLMETHYL OR ARYLSULFONAMIDE SUBSTITUTED AROMATIC COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MADULATION OF THE DOPAMINE D3 RECEPTOR
Document Type and Number:
WIPO Patent Application WO2006040178
Kind Code:
A9
Abstract:
The present invention relates to aromatic compounds of the formula (I), wherein Ar is phenyl or an aromatic 5- or 6-membered C-bound heteroaromatic radical, wherein Ar may carry 1 radical Ra and wherein Ar may also carry 1 or 2 radicals Rb; X is N or CH; Y is O, S, -CH=N-, -CH=CH- or -N=CH-; A is CH2i O or S; E is CR6R7 or NR 3; R1 is C1-C4-alkyl, C3-C4-cycloalkyl, C3-C4-cycloalkylmethyl, C3-C4-alkenyl, fluorinated C1-C4-alkyl, fluorinated C3-C4-cycloalkyl, fluorinated C3-C4-cycloalkylmethyl, fluorinated C3-C4-alkenyl, formyl or C,-C3-alkylcarbonyl; R1a is H, C2-C4-alkyl, C3-C4-cycloalkyl, C3-C4-alkenyl, fluorinated C1-C4-alkyl, fluorinated C3-C4 -cycloalkyl, or R1a and R2 together are (CH2)n with n being 2 or 3, or R1
Inventors:
DRESCHER KARLA (DE)
HAUPT ANDREAS (DE)
UNGER LILIANE (DE)
TURNER SEAN C (DE)
BRAJE WILFRIED (DE)
GRANDEL ROLAND (DE)
HENRY CHRISTOPHE (DE)
HAUPT ANDREAS (DE)
UNGER LILIANE (DE)
TURNER SEAN C (DE)
BRAJE WILFRIED (DE)
GRANDEL ROLAND (DE)
HENRY CHRISTOPHE (DE)
Application Number:
PCT/EP2005/011091
Publication Date:
April 19, 2007
Filing Date:
October 14, 2005
Export Citation:
Assignee:
ABBOTT GMBH & CO KG (DE)
DRESCHER KARLA (DE)
HAUPT ANDREAS (DE)
UNGER LILIANE (DE)
TURNER SEAN C (DE)
BRAJE WILFRIED (DE)
GRANDEL ROLAND (DE)
HENRY CHRISTOPHE (DE)
DRESCHER KARLA (DE)
HAUPT ANDREAS (DE)
UNGER LILIANE (DE)
TURNER SEAN C (DE)
BRAJE WILFRIED (DE)
GRANDEL ROLAND (DE)
HENRY CHRISTOPHE (DE)
International Classes:
C07D311/04; A61K31/13; A61K31/35; A61K31/47; A61P25/16; C07C211/19; C07D215/38
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