Title:
ASYMMETRIC PES FILTER MEMBRANE FOR VIRUS REMOVAL AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/040973
Kind Code:
A1
Abstract:
Provided in the present invention are an asymmetric PES filter membrane for virus removal and a preparation method therefor. The PES filter membrane comprises a main body, the main body having a non-oriented tortuous path therein, one side surface of the main body being a first outer surface, and an average pore diameter of the first outer surface being 150-450 nm, it being a large pore surface; another side surface of the main body is a second outer surface, the second outer surface having an average pore diameter 10-42nm, it being a small pore surface; the average pore diameter of the main body varies in a continuous gradient from a region near the first outer surface to a region near the second outer surface. The main body comprises a pre-filter layer and a separation layer used to trap viruses, another side of the pre-filter layer and another side of the separation layer being transitioned with continuous fibers. The PES filter membrane is prepared by means of a single-casting solution, is integrally formed, and does not need to be compounded, and the preparation process is relatively simple. In addition, the prepared PES filter membrane has a strong trapping effect on parvoviruses having a particle size of 20 nm or more, and can obtain a high protein yield, thereby meeting practical application requirements.
Inventors:
JIA ANDY (CN)
LU ALBERT (CN)
LU ALBERT (CN)
Application Number:
PCT/CN2022/119073
Publication Date:
March 23, 2023
Filing Date:
September 15, 2022
Export Citation:
Assignee:
HANGZHOU COBETTER FILTRATION EQUIPMENT CO LTD (CN)
International Classes:
B01D67/00; B01D69/02; B01D71/68
Foreign References:
| CN113842792A | 2021-12-28 | |||
| CN113856495A | 2021-12-31 | |||
| CN106573203A | 2017-04-19 | |||
| US20120076934A1 | 2012-03-29 |
Attorney, Agent or Firm:
HANGZHOU CHUANGZHIZHUOYING INTELLECTUAL PROPERTY AGENCY ( GENERAL PARTNERSHIP) (CN)
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