Title:
AUTOANTIBODY BIOMARKER FOR DIAGNOSING DEMENTIA AND METHOD FOR DIAGNOSING DEMENTIA BY USING SAME
Document Type and Number:
WIPO Patent Application WO/2018/038352
Kind Code:
A2
Abstract:
The present invention relates to an autoantibody biomarker for diagnosing dementia and a kit for diagnosing dementia comprising the same. In particular, the present invention relates to an autoantibody biomarker that selectively recognizes Ataxia, Cerebellar, Cayman Type (ATCAY), NME/NM23 Family Member 7 (NME7) and Nucleolar Protein 3 (NOL3) which can be used for the diagnosis of dementia as the amounts thereof are specifically increased in the blood of a dementia patient compared to a normal person, and a diagnostic kit for diagnosing dementia comprising an antigen recognizing the same. The dementia diagnostic kit including the autoantibodies of ATCAY, NME7 and NOL3 which can be used as a marker for diagnosing dementia of the present invention can diagnose dementia very easily by using the blood of a patient, and thus can effectively be used for early diagnosis of dementia.
Inventors:
JEON JAE PIL (KR)
SHIM SUNG MI (KR)
SONG JIHYUN (KR)
SHIM SUNG MI (KR)
SONG JIHYUN (KR)
Application Number:
PCT/KR2017/004836
Publication Date:
March 01, 2018
Filing Date:
May 10, 2017
Export Citation:
Assignee:
KOREA CENTER DISEASE CONTROL & PREVENTION (KR)
International Classes:
G01N33/68; G01N33/543; G01N33/558
Attorney, Agent or Firm:
LEE, Won Hee (KR)
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