Title:
AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY
Document Type and Number:
WIPO Patent Application WO/2018/214866
Kind Code:
A9
Abstract:
An azaaryl derivative having a structure of formula (I), a preparation method therefor, and an application thereof for use in pharmacy. The series of compounds of the present invention can be widely applied to the preparation of drugs for treating cancer, tumor, autoimmune diseases, metabolic diseases, or metastatic diseases, in particular for treating ovarian cancer, pancreatic cancer, prostate cancer, breast cancer, cervical cancer, glioblastoma, multiple myeloma, metabolic diseases, neurodegenerative diseases, metastasis of primary tumor sites, or bone metastatic cancers, and are expected to be developed into a new generation of CSF1R inhibitor drugs.
Inventors:
ZHAO BAOWEI (CN)
ZHANG MINGMING (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
ZHANG MINGMING (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2018/087806
Publication Date:
December 27, 2018
Filing Date:
May 22, 2018
Export Citation:
Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
C07D401/14; A61K31/4375
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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