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Title:
B7H6 ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/104062
Kind Code:
A1
Abstract:
Disclosed are a B7H6 antibody and a use thereof. The antibody comprises a heavy-chain CDR1, a heavy-chain CDR2 and a heavy-chain CDR3, and a light-chain CDR1, a light-chain CDR2 and a light-chain CDR3. The antibody of the present invention can bind to B7H6, thus promoting the binding of B7H6 to the NK cell activating receptor NKp30, and has an anti-cancer function.

Inventors:
TIAN ZHIGANG (CN)
CAO GUOSHUAI (CN)
XIAO WEIHUA (CN)
SUN RUI (CN)
SUN HAOYU (CN)
Application Number:
PCT/CN2022/137095
Publication Date:
June 15, 2023
Filing Date:
December 07, 2022
Export Citation:
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Assignee:
HEFEI TG IMMUNOPHARMA CO LTD (CN)
International Classes:
C07K16/28; A61K39/395; A61K47/68; A61P31/00; A61P35/00; A61P37/06; C12N5/07; C12N15/11; C12N15/13; C12N15/63; G01N33/574; G01N33/577; G01N33/68
Domestic Patent References:
WO2013169691A12013-11-14
WO2009046407A22009-04-09
Foreign References:
CN114395045A2022-04-26
CN109310764A2019-02-05
DE602010019061T2
US20210107983A12021-04-15
CN202111485380A2021-12-07
Other References:
COLOMA, J.J. ET AL., BIOTECHNIQUES, vol. 11, 1991, pages 152 - 156
CHOTHIALESK, J.MOL.BIOL., vol. 196, 1987, pages 901 - 917
LARRICK, J.W ET AL., SCAND. J. IMMUNOL., vol. 32, 1990, pages 121 - 128
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (CN)
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