Title:
BACILLUS COAGULANS STRAIN WITH HIGH POLYAMINE PRODUCTION
Document Type and Number:
WIPO Patent Application WO/2024/014882
Kind Code:
A1
Abstract:
The present invention relates to: a Bacillus coagulans PA strain for producing a large amount of polyamine; and a polyamine preparation method using same. The Bacillus coagulans PA strain of the present invention proliferates in anaerobic intestines and can consistently produce a large amount of polyamine and supply same to the human body when spores, themselves, are ingested, and thus the strain, spores thereof, culture products thereof or fermentation products thereof, of the present invention, can be applied and used as a food, a feed and the like that can produce polyamine, especially spermidine, with high efficiency, and can also be effectively used as a functional material for hair growth promotion and skin improvement.
Inventors:
RHEE HAE IK (KR)
RHEE DO YOUNG (KR)
KIM HEE WOONG (KR)
RHEE DO YOUNG (KR)
KIM HEE WOONG (KR)
Application Number:
PCT/KR2023/009974
Publication Date:
January 18, 2024
Filing Date:
July 12, 2023
Export Citation:
Assignee:
RHEE HAE IK (KR)
RHEE DO YOUNG (KR)
RHEE DO YOUNG (KR)
International Classes:
C12N1/20; A23K10/16; A23L33/135; A61K8/99; A61P17/00; A61Q7/00; A61Q19/00; C12P13/00; C12R1/07
Domestic Patent References:
| WO2023281787A1 | 2023-01-12 |
Foreign References:
| KR101794772B1 | 2017-12-01 | |||
| KR20200099308A | 2020-08-24 | |||
| KR101373224B1 | 2014-03-11 | |||
| KR101760766B1 | 2017-07-24 | |||
| KR20220045692A | 2022-04-13 |
Other References:
SUZUKI, HIDEYUKI; FUJIWARA, YUKI; THONGBHUBATE, KULLATHIDA; MAEDA, MASAHIRO: "4A08-05 Discovery of a spore-forming lactic acid bacterium bacillus coagulans that synthesizes and excretes spermidine into the extracellular space under anaerobic conditions. ", PROCEEDINGS OF THE ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY (JSBBA 2022); MARCH 15-18, 2022, vol. 2022, 18 March 2022 (2022-03-18) - 18 March 2022 (2022-03-18), pages 1000, XP009552682
FUJIWARA, YUKI; MATSUURA, KENTO; HARAGUCHI, KENJI; SUZUKI, HIDEYUKI: "3A09a13 Biosynthetic pathway of polyamines of Bacillus coagulans", ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY; MARCH 25 - 28, 2020, vol. 2020, 5 March 2020 (2020-03-05) - 28 March 2020 (2020-03-28), pages 698, XP009542767
DATABASE Nucleotide 4 June 2018 (2018-06-04), ANONYMOUS : "Bacillus coagulans LA204, complete genome", XP093129471, retrieved from NCBI Database accession no. CP025437.1
FUJIWARA, YUKI; MATSUURA, KENTO; HARAGUCHI, KENJI; SUZUKI, HIDEYUKI: "3A09a13 Biosynthetic pathway of polyamines of Bacillus coagulans", ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY; MARCH 25 - 28, 2020, vol. 2020, 5 March 2020 (2020-03-05) - 28 March 2020 (2020-03-28), pages 698, XP009542767
DATABASE Nucleotide 4 June 2018 (2018-06-04), ANONYMOUS : "Bacillus coagulans LA204, complete genome", XP093129471, retrieved from NCBI Database accession no. CP025437.1
Attorney, Agent or Firm:
WIE, Byoung-Gap (KR)
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