Title:
BACKGROUD LIGHT REDUCING METHOD IN EVANSCENT WAVE EXCITING FLUORESCENT OSERVATION, AND COMPONENT THEREFOR
Document Type and Number:
WIPO Patent Application WO/2008/029591
Kind Code:
A1
Abstract:
In an evanescent wave exciting fluorescent observation, stray light arriving at
a probe solution layer on an upper layer of a fixing region of molecules under examination
in a reaction chamber is effectively absorbed by disposing a stray light absorptive
region on a waveguide substrate, so that the stay light is suppressed to enter
into the reaction chamber and the scattering stray light is suppressed to occur
at an edge surface of the waveguide substrate made by applying a laser cutting
process to the edge surface of the waveguide substrate on which light is incident.
With the structure, critical background fluorescence at the evanescent wave
exciting fluorescent observation is significantly reduced.
Inventors:
HIRABAYASHI, Jun (Tsukuba Central 2 1-1, Umezono 1-chom, Tsukuba-shi Ibaraki 68, 3058568, JP)
平林 淳 (〒68 茨城県つくば市梅園１－１－１中央第２ 独立行政法人産業技術総合研究所内 Ibaraki, 3058568, JP)
平林 淳 (〒68 茨城県つくば市梅園１－１－１中央第２ 独立行政法人産業技術総合研究所内 Ibaraki, 3058568, JP)
Application Number:
JP2007/065708
Publication Date:
March 13, 2008
Filing Date:
August 10, 2007
Export Citation:
Assignee:
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (3-1 Kasumigaseki 1-chome, Chiyoda-ku Tokyo, 21, 1008921, JP)
独立行政法人産業技術総合研究所 (〒21 東京都千代田区霞が関１丁目３番１号 Tokyo, 1008921, JP)
HIRABAYASHI, Jun (Tsukuba Central 2 1-1, Umezono 1-chom, Tsukuba-shi Ibaraki 68, 3058568, JP)
独立行政法人産業技術総合研究所 (〒21 東京都千代田区霞が関１丁目３番１号 Tokyo, 1008921, JP)
HIRABAYASHI, Jun (Tsukuba Central 2 1-1, Umezono 1-chom, Tsukuba-shi Ibaraki 68, 3058568, JP)
International Classes:
G01N21/64; G01N21/64