Title:
BACTERIOPHAGE COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2021/079435
Kind Code:
A1
Abstract:
This composition is for lysing Staphylococcus aureus or treating or preventing diseases caused by Staphylococcus aureus, and contains, as active ingredients, at least one bacteriophage selected from the group consisting of the bacteriophage specified by Deposit No. NITE BP-693 and the bacteriophage specified by Deposit No. NITE BP-694, and an endolysin, which is at least one protein selected from the group consisting of (a) a protein having the amino acid sequence described in SEQ ID NO: 1, (b) proteins having amino acid sequences having at least 80% identity with the amino acid sequence described in SEQ ID NO: 1, and (c) proteins having amino acid sequences obtained by providing at least one amino acid substitution, deletion, addition, and/or insertion to the amino acid sequence described in SEQ ID NO: 1.
Inventors:
IWANO HIDETOMO (JP)
HIGUCHI HIDETOSHI (JP)
TAMURA YUTAKA (JP)
USUI MASARU (JP)
FUJIKI JUMPEI (JP)
HIGUCHI HIDETOSHI (JP)
TAMURA YUTAKA (JP)
USUI MASARU (JP)
FUJIKI JUMPEI (JP)
Application Number:
PCT/JP2019/041541
Publication Date:
April 29, 2021
Filing Date:
October 23, 2019
Export Citation:
Assignee:
MEIJI SEIKA PHARMA CO LTD (JP)
INCORPORATED EDUCATIONAL INST RAKUNO GAKUEN (JP)
INCORPORATED EDUCATIONAL INST RAKUNO GAKUEN (JP)
International Classes:
A61K35/76; A61K38/46; A61P1/00; A61P7/00; A61P11/00; A61P13/02; A61P15/00; A61P17/00; A61P19/02; A61P25/00; A61P27/00; A61P27/02; A61P31/04; C07K14/00; C12N7/00
Foreign References:
| JP2011050373A | 2011-03-17 |
Other References:
FUJIKI, J. ET AL.: "Characterization of the Lytic Capability of a LysK-Like Endolysin, Lys-phiSA012, Derived from a Polyvalent Staphylococcus aureus Bacteriophage", PHARMACEUTICALS, vol. 11, no. 1, 24 February 2018 (2018-02-24), pages 25, XP055819272
Attorney, Agent or Firm:
CENTCREST IP ATTORNEYS (JP)
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