Title:
BACTERIOPHAGE-CONTAINING THERAPEUTIC AGENTS
Document Type and Number:
WIPO Patent Application WO2005009451
Kind Code:
A9
Abstract:
The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa.Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.
Inventors:
SOOTHILL JAMES (GB)
HAWKINS CATHERINE (GB)
HARPER DAVID (GB)
HAWKINS CATHERINE (GB)
HARPER DAVID (GB)
Application Number:
PCT/GB2004/003237
Publication Date:
May 18, 2006
Filing Date:
July 23, 2004
Export Citation:
Assignee:
BIOCONTROL LTD (GB)
SOOTHILL JAMES (GB)
HAWKINS CATHERINE (GB)
HARPER DAVID (GB)
SOOTHILL JAMES (GB)
HAWKINS CATHERINE (GB)
HARPER DAVID (GB)
International Classes:
A61K31/424; A61K31/43; A61K35/76; A61P31/00; (IPC1-7): A61K35/76; A61K31/424; A61K31/43; A61K35/74; A61P31/00
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