Title:
BASE MATERIAL FOR FORMING LUMEN-SHAPED TISSUE WITH VALVE, METHOD FOR PRODUCING LUMEN-SHAPED TISSUE WITH VALVE, AND ARTIFICIAL BLOOD VESSEL WITH VALVE
Document Type and Number:
WIPO Patent Application WO/2012/067137
Kind Code:
A1
Abstract:
The present invention provides a base material which enables the formation of a lumen-shaped tissue with valve, said lumen-shaped tissue comprising an enlarged part and a valve that are formed of a biological tissue. More specifically, the base material comprises a first column member (5) forming the upstream tubular part (4) of a blood vessel (3), a second column member (7) forming the downstream tubular part (6) of the blood vessel (3), a plurality of enlarged members (10) forming the enlarged part (8) and valve lobes (9) of the blood vessel (3), and a lock means (11) locking the enlarged members (10) to the first column member (5) and/or the second column member (7). The lock means (11) comprises concavities (15a, 15b) to be in contact with the end faces, in the axial direction, of the first column member (5) and/or the second column member (7) and a lock part (18) projecting from the main body (17) of the enlarged member and locking to the concavity. The outer circumferential face of the main body (17) of the enlarged member (10) constitutes an enlarged part-forming face (20) and a space between the main body (17) of the enlarged member and the first column member (5) and/or the second column member (7) constitutes a valve lobe-forming part (22).
Inventors:
NAKAYAMA YASUHIDE
OIE TOMONORI
OIE TOMONORI
Application Number:
PCT/JP2011/076372
Publication Date:
May 24, 2012
Filing Date:
November 16, 2011
Export Citation:
Assignee:
NAT CEREBRAL & CARDIOVASCULAR CT (JP)
NAKAYAMA YASUHIDE
OIE TOMONORI
NAKAYAMA YASUHIDE
OIE TOMONORI
International Classes:
A61F2/06; A61F2/24; A61L27/00
Foreign References:
| JP2009539439A | 2009-11-19 | |||
| JP2006524119A | 2006-10-26 | |||
| JP2010088625A | 2010-04-22 | |||
| JP2007037764A | 2007-02-15 | |||
| JP2007312821A | 2007-12-06 | |||
| JP2008237896A | 2008-10-09 | |||
| JP2010094476A | 2010-04-30 | |||
| JP2006314601A | 2006-11-24 |
Other References:
See also references of EP 2641565A4
ANTIA MOL ET AL.: "Autologous Human Tissue-Engineered Heart Valves", CIRCULATION, 4 July 2006 (2006-07-04), pages 1 - 152,158
ANTIA MOL ET AL.: "Autologous Human Tissue-Engineered Heart Valves", CIRCULATION, 4 July 2006 (2006-07-04), pages 1 - 152,158
Attorney, Agent or Firm:
OHSHIMA, Yasutoshi et al. (JP)
Yasuo Oshima (JP)
Yasuo Oshima (JP)
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Claims:
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