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Title:
BASIC AMINE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2005/085209
Kind Code:
A1
Abstract:
A novel amine compound represented by the following general formula (1), which is effective in HIV viral infectious diseases and diseases such as rheumatism or cancer metastasis. [Chemical formula 1] (1) Typically, A1 and A2 each represents hydrogen or an optionally substituted, monocyclic or polycyclic, heteroaromatic ring and W represents an optionally substituted benzene ring or a group represented by the following (10) or (11). [Chemical formula 2] (10) [Chemical formula 3] (11) X represents oxygen, CH2, C(=O), NR11, or CHR35 and D represents a group represented by the following formula (6). [Chemical formula 4] (6) In the formula (6), Q represents a single bond, NR12, or the formula (13): [Chemical formula 5] (13) Y represents a group represented by the following formula (7): [Chemical formula 6] or (7) (wherein Z represents an optionally substituted, monocyclic or polycyclic aromatic ring), and B represents -NR25R26. In these formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl, or alkynyl.

Inventors:
SAITOU ATSUSHI (JP)
KIKUMOTO SHIGEYUKI (JP)
ONO MASAHIRO (JP)
MATSUI RYO (JP)
YAMAMOTO MASASHI (JP)
SAWA TOMOHIRO (JP)
SUZUKI SHIGERU (JP)
YANAKA MIKIRO (JP)
Application Number:
PCT/JP2005/004189
Publication Date:
September 15, 2005
Filing Date:
March 10, 2005
Export Citation:
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Assignee:
KUREHA CHEMICAL IND CO LTD (JP)
SAITOU ATSUSHI (JP)
KIKUMOTO SHIGEYUKI (JP)
ONO MASAHIRO (JP)
MATSUI RYO (JP)
YAMAMOTO MASASHI (JP)
SAWA TOMOHIRO (JP)
SUZUKI SHIGERU (JP)
YANAKA MIKIRO (JP)
International Classes:
A61K31/4035; A61K31/417; A61K31/4178; A61K31/4184; A61K31/4188; A61K31/428; A61K31/4439; A61K31/4709; A61K31/4725; A61K31/5513; A61P29/00; A61P31/12; A61P31/18; A61P35/00; A61P35/04; A61P43/00; C07D233/64; C07D401/12; C07D403/06; C07D403/14; C07D405/14; C07D417/14; C07D471/04; (IPC1-7): C07D233/64; A61K31/4035; A61K31/417; A61K31/4178; A61K31/4184; A61K31/4188; A61K31/428; A61K31/4439; A61K31/4709; A61K31/4725; A61K31/5513; A61P29/00; A61P31/12; A61P31/18; A61P35/00; A61P35/04; A61P43/00; C07D401/12; C07D403/06; C07D403/14; C07D405/14; C07D417/14; C07D471/04
Domestic Patent References:
WO2003029218A12003-04-10
WO2002094261A12002-11-28
WO2002022600A22002-03-21
WO2000056729A12000-09-28
WO2004024697A12004-03-25
Other References:
None
See also references of EP 1724263A4
Attorney, Agent or Firm:
Fujino, Seiya (7-7 Toranomon 2-chom, Minato-ku Tokyo 01, JP)
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