Title:
BCNU SUSTAINED-RELEASE IMPLANT FOR TREATING SOLID TUMOR AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/095592
Kind Code:
A1
Abstract:
A BCNU sustained-release implant for treating solid tumor and preparation method thereof, the sustained-release implant comprising a sustained-release excipient and an effective anti-cancer ingredient BCNU; the sustained-release excipient is made from a copolymer of lactide and glycolide having a viscosity in a range of 0.3-0.6 dl/g; the percentage by weight of the BCNU is 7.5%-30%; the mass ratio of lactide to glycolide is (25-75) : (75-25). The implant is applied to treat solid tumors such as pancreatic cancer, lung cancer and the like, and liver and brain metastatic tumors.
Inventors:
KONG QINGZHONG (CN)
WEI MINGXING (CN)
SU HONGQING (CN)
WU SONGZHI (CN)
YU JIANJIANG (CN)
JIANG JUNMIN (CN)
LI ZHAOWEN (CN)
WEI MINGXING (CN)
SU HONGQING (CN)
WU SONGZHI (CN)
YU JIANJIANG (CN)
JIANG JUNMIN (CN)
LI ZHAOWEN (CN)
Application Number:
PCT/CN2015/091049
Publication Date:
June 23, 2016
Filing Date:
September 29, 2015
Export Citation:
Assignee:
SHANDONG LANJIN PHARMACEUTICALS CO LTD (CN)
International Classes:
A61K9/00; A61K31/175; A61K47/34
Foreign References:
| CN104523566A | 2015-04-22 | |||
| CN1698592A | 2005-11-23 | |||
| CN101176713A | 2008-05-14 |
Attorney, Agent or Firm:
JINAN JINDI INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
济南金迪知识产权代理有限公司 (CN)
济南金迪知识产权代理有限公司 (CN)
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