BENZAMIDE COMPOUND AND USE THEREOF - WUHAN HUMANWELL INNOVATIVE DRUG RES AND DEVELOPMENT CENTER LIMITED COMPANY

Title:

BENZAMIDE COMPOUND AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/068930

Kind Code:

A1

Abstract:

The present invention relates to a novel compound, which effectively antagonizes P2X3 receptors and is represented by formula (I), a tautomer, stereoisomer, hydrate, solvate, pharmaceutically acceptable salt or prodrug thereof, and a preparation method and a use thereof in the preparation of drugs.

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WO/2023/094827	SPIROCYCLIC CAV2.3 ANTAGONISTS
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Inventors:

ZHANG XUEJUN (CN)
ZANG YANG (CN)
LI XUEQIANG (CN)
YANG CHENGBING (CN)
WANG YONGGANG (CN)
ZHANG BO (CN)
LI YANG (CN)
LIU LIFEI (CN)
YANG JUN (CN)
LI LIE (CN)

Application Number:

PCT/CN2021/122232

Publication Date:

April 07, 2022

Filing Date:

September 30, 2021

Export Citation:

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Assignee:

WUHAN HUMANWELL INNOVATIVE DRUG RES AND DEVELOPMENT CENTER LIMITED COMPANY (CN)

International Classes:

C07D417/12; A61K31/427; A61K31/501; A61K31/506; A61P13/00; A61P13/08; A61P25/04; A61P25/28; A61P29/00; C07D417/14

Domestic Patent References:

WO2019219672A1	2019-11-21
WO2019219674A1	2019-11-21
WO2020260463A1	2020-12-30
WO2016091776A1	2016-06-16

Foreign References:

CN107207507A	2017-09-26
CN202011059868A	2020-09-30
CN202110296983A	2021-03-19

Other References:

MAEHR, J. CHEM. ED., vol. 62, 1985, pages 114 - 120

Attorney, Agent or Firm:

ZHIFAN & PARTNERS (CN)

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